Dimensional approach to delusions in psychotic depression in the elderly: factor structure and clinical correlates

Gournellis, Rossetos; Oulis, Panagiotis; Michalopoulou, Panayiota G.; Kaparoudaki, Adamantia; Dimitrakopoulos, Christos; Lykouras, Lefteris

doi:10.1002/gps.2130

Cited by 9 publications

(2 citation statements)

References 27 publications

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“…After post-hoc correction, no significant anamnestic or clinical determinant other than depressive severity resulted to impact over the emergence of dysfunctional beliefs. 13 , 25 , 30 , 31 ) Severity of depression has been proved to be associated with more severely distorted negative cognitions, which in turn may predict the emergence of psychotic symptoms, 13 ) however this multivariate analysis may hide the clinical univariate correlations, therefore we reported both.…”

Section: Discussionmentioning

confidence: 86%

Dimensions of Delusions in Major Depression: Socio-demographic and Clinical Correlates in an Unipolar-Bipolar Sample

Zaninotto

Souery²,

Calati

et al. 2015

Clin Psychopharmacol Neurosci

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ObjectiveThe present study aims at exploring associations between a continuous measure of distorted thought contents and a set of demographic and clinical features in a sample of unipolar/bipolar depressed patients.MethodsOur sample included 1,833 depressed subjects. Severity of mood symptoms was assessed by the 21 items Hamilton Depression Rating Scale (HAM-D). The continuous outcome measure was represented by a delusion (DEL) factor, extracted from HAM-D items and including items: 2 (“Feelings of guilt”), 15 (“Hypochondriasis”), and 20 (“Paranoid symptoms”). Each socio-demographic and clinical variable was tested by a generalized linear model test, having depressive severity (HAM-D score–DEL score) as the covariate.ResultsA family history of major depressive disorder (MDD; p=0.0006), a diagnosis of bipolar disorder, type I ( p=0.0003), a comorbid general anxiety disorder (p<0.0001), and a higher number of manic episodes during lifetime (p<0.0001), were all associated to higher DEL scores. Conversely, an older age at onset (p<0.0001) and a longer duration of hospitalization for depression over lifetime (p=0.0003) had a negative impact over DEL scores. On secondary analyses, only the presence of psychotic features (p<0.0001) and depressive severity (p<0.0001) were found to be independently associated to higher DEL scores.ConclusionThe retrospective design and a non validated continuous measure for distorted thought contents were the main limitations of our study. Excluding the presence of psychotic features and depressive severity, no socio-demographic or clinical variable was found to be associated to our continuous measure of distorted thinking in depression.

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Section: Discussionmentioning

confidence: 86%

Dimensions of Delusions in Major Depression: Socio-demographic and Clinical Correlates in an Unipolar-Bipolar Sample

Zaninotto

Souery²,

Calati

et al. 2015

Clin Psychopharmacol Neurosci

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“…Four of them were double‐blind randomized controlled studies and were rated as high‐quality studies (Meyers et al ., ; Mulsant et al ., ; Meyers et al ., ;Flint et al ., ), whereas 19 were open prospective controlled ones and were rated as medium‐quality studies (Kivela and Pahkala, ; Meyers et al ., ; Baldwin, ; Zubenko et al ., ; O'Brien et al ., ; Flint and Rifat, , ; Kim et al ., ; Simpson et al ., ; Meyers et al ., ; Gournellis et al ., ; Ohayon and Schatzberg, ; Lykouras et al ., ; Lee et al ., ; Parker et al ., ; Kessing, ; Kok et al ., ; Flint et al ., ; Gournellis et al ., ). Twelve were rated as low‐quality studies—always in regard to our research questions—because four were retrospective (Baldwin and Jolley, ; Meyers and Greenberg, ; Baldwin, ; Nelson et al ., ), three had a small number of PMD patients (Kunik et al ., , eight patients; Grierz et al ., , 10 patients; Politis et al ., , 11 patients), two (Murphy, ; Burvuil et al ., ) did not directly compare PMD and non‐PMD patients, one (Gournellis et al ., ) lacked a control group, one (Meyers et al ., ) did not compare older and younger PMD patients and one (Navaro et al ., ) had doubtful relevance to our research questions (Table ).…”

Section: Resultsmentioning

confidence: 99%

Psychotic major depression in older people: a systematic review

Gournellis

Oulis

Howard

2014

Int J Geriat Psychiatry

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Current awareness in geriatric psychiatry

2009

Int J Geriat Psychiatry

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of geriatric psychiatry. Each bibliography is divided into 9 sections: 1 Reviews; 2 General; 3 Assessment; 4 Epidemiology; 5 Therapy; 6 Care; 7 Dementia; 8 Depression; 9 Psychology. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted

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Dimensional approach to delusions in psychotic depression in the elderly: factor structure and clinical correlates

Cited by 9 publications

References 27 publications

Dimensions of Delusions in Major Depression: Socio-demographic and Clinical Correlates in an Unipolar-Bipolar Sample

Dimensions of Delusions in Major Depression: Socio-demographic and Clinical Correlates in an Unipolar-Bipolar Sample

Psychotic major depression in older people: a systematic review

Current awareness in geriatric psychiatry

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