Dimensional characterization of gold nanorods by combining millisecond and microsecond temporal resolution single particle ICP-MS measurements

Abstract

By combining normal and high temporal resolution spICP-MS measurements, the accurate dimensional analysis of nanorods is possible.

Contribution to Accurate Spherical Gold Nanoparticle Size Determination by Single-Particle Inductively Coupled Mass Spectrometry: A Comparison with Small-Angle X-ray Scattering

“…It can theorized from this result that only an outer shell of the gold core is evaporated, ionized and thus analyzed or that just of an external portion of the ionic cloud is measured by the detector. It has to be pointed out that this 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 12 result is coherent with a recent study demonstrating that SPICPMS is sensitive to nanoparticle shape 30 .…”

“…On the other hand, Single Particle ICPMS (SPICPMS) is still under developments and requires involved process clarification and accuracy improvement. The strategy of this study is the comparison of the two techniques to study comprehensively SPICPMS performance and observe phenomena otherwise hidden.6 spherical gold nanoparticle suspensions distributed over a large size range (30, 50, 60, 80,100 and150 nm) are studied as standards. Potential matrix effect are eliminated by stabilizing nanoparticles with chitosan in HCL.…”

“…6 spherical gold nanoparticle suspensions distributed over a large size range (30, 50, 60, 80,100 and150 nm) are studied as standards. Potential matrix effect are eliminated by stabilizing nanoparticles with chitosan in HCL.…”

Porosity determination of nano- and sub-micron particles by single particle inductively coupled plasma mass spectrometry

“…Through the evaluation of the signal histograms, the technique can provide information about the presence, size distribution, number concentration, elemental or isotopic composition of nanoparticles [21][22][23][24]. In our previous studies, we demonstrated that not only single component or homogenous (random) alloy spherical NPs can be analyzed, and additional information, such as the structure and aspect ratio, can also be obtained by the spICP-MS method [25,26]. The spICP-MS analysis is fast (takes only a couple of minutes) and the required sample volume is small (a few mL).…”

“…This information can then be combined with particle diameter or volume data from other NP characterization techniques, such as electron microscopy or dynamic light scattering, towards the calculation of the total pore (void) were optimized prior to the measurements. Plasma sampling depth was optimized using the signal-to-noise ratio as objective function [25]. Dwell time (called integration time in the Agilent nomenclature) was decreased for 28 Si in order to lower the contribution of background to the measured signal.…”