Diminished expression of B antigen mimicking B3 phenotype in a patient with AML-M3: a rare case report

Preventing misinterpretation of rare blood types in clinical laboratories: A case study on B3 phenotype

“…Accurate determination of an individual's blood group is critically important because small mistakes may result in lifethreatening transfusion reactions. 1 The weak expression of A, B, and H antigens on the red blood cell surface can be either inherited or acquired. B subgroups are exceedingly rare, occurring less frequently than A subgroups, and are classified in descending order of B antigen quantity as B3, Bx, Bm, and Bel.…”

“…B subgroups are exceedingly rare, occurring less frequently than A subgroups, and are classified in descending order of B antigen quantity as B3, Bx, Bm, and Bel. 1 The B3 phenotype has been identified as the most common subgroup among Taiwanese individuals. [2][3][4] In the Chinese population, the B3 blood type is the most prevalent B subtype, occurring at a frequency of 1 in 900.…”