2010
DOI: 10.1002/hed.21373
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Diminishing diagnosis of follicular thyroid carcinoma

Abstract: The proportion of follicular cancers is less than traditionally reported. This change is due to an increased incidence of papillary cancers, and modifications of the histologic criteria used for classification of encapsulated follicular lesions. There are potential prognostic consequences, as follicular cancers have been perceived as more aggressive.

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Cited by 20 publications
(14 citation statements)
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“…, 20 using as a threshold the size of 1 cm for primary tumour diameter, found an exponentially increased risk of more advanced disease with greater size for both PTC and FTC. Our data corroborate results of previous studies (although not all) showing the dramatic reduction in the frequency of FTC and the subsequently increased proportion of PTC 13,21 . In group I, FTC represented 25% of the DCT, but in group IV only 6·5% were FTC.…”
Section: Discussionsupporting
confidence: 92%
“…, 20 using as a threshold the size of 1 cm for primary tumour diameter, found an exponentially increased risk of more advanced disease with greater size for both PTC and FTC. Our data corroborate results of previous studies (although not all) showing the dramatic reduction in the frequency of FTC and the subsequently increased proportion of PTC 13,21 . In group I, FTC represented 25% of the DCT, but in group IV only 6·5% were FTC.…”
Section: Discussionsupporting
confidence: 92%
“…The reporting rate of NIFTP on histopathology is quite variable in the published data, which may be caused by multiple factors, including patient demographics, referral patterns, and the diagnostic threshold of individual cytopathologists and surgical pathologists. Currently, FVPTC represents a significant proportion (approximately 15%‐20%) of PTC diagnoses with increasing incidence . With the nomenclature change from NI‐FVPTC to NIFTP, a significant fraction of these PTCs will be excluded from classification as malignant .…”
Section: Discussionmentioning
confidence: 99%
“…FTC currently represents 10% or less of thyroid cancer cases diagnosed in children or young adults (8,50,(358)(359)(360), and the prevalence of true FTC appears to be decreasing over time (361). FTC is most commonly diagnosed in adolescents, and there is less of a female to male preponderance compared with PTC (9,11,50,51,226).…”
Section: Recommendation Rating: C [E1] Follicular Thyroid Cancermentioning
confidence: 99%