Diminution of β-Glucuronidase Activity in Post-Heparin Human Sera

Bartalos, Mihály; Györkey, Ferenc; Koppányi, Zsolt

doi:10.1038/195181a0

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Formation Of "Complexes"1

Function Of Beta‐glucuronidase1

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1963

1974

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Cited by 7 publications

(2 citation statements)

References 6 publications

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“…77 ,95 Both inhibitor and substrate compete for the same energy sites; an increase in ionic strength decreases the inhibitory effect of heparin and chondroitin sulfate B.95 Serum beta-glucuronidase activity is decreased 43 to 64 per cent in human postheparin sera. 14 Beta-glucuronidase shows a two thousand fold greater affinity for heparin than for phenolphthalein .beta -glucuronide. 27 Nonspecific stimulation of tyrosine-alpha ketoglutarate transaminase activity in vivo by heparin, chondroitin sulfate, and a number of other agents has been observed.…”

Section: Formation Of "Complexes"mentioning

confidence: 99%

Some side effects of heparin, heparinoids, and their antagonists

Coon

Willis

1966

Clin Pharma and Therapeutics

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Section: Formation Of "Complexes"mentioning

confidence: 99%

Some side effects of heparin, heparinoids, and their antagonists

Coon

Willis

1966

Clin Pharma and Therapeutics

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“…Other investigators (127) have suggested a role in bilirubin metabolism. Beta‐glucuronidase activity diminishes in the patient's serum after heparin administration (128); treatment with heparin also results in the appearance of lipoprotein lipase in serum. Kayahan (129) described an inverse relationship between serum beta‐glucuronidase activity and arteriosclerosis.…”

Section: Function Of Beta‐glucuronidasementioning

confidence: 99%

Beta‐glucuronidases: Their Significance and Relation to Cancer*

Bartalos

Györkey

1963

J American Geriatrics Society

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From cell biology to immunology—A short trip

Herzenberg

1970

Journal Cellular Physiology

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Immunologic memory and immunoglobulin allotype suppression are discussed as problems in Cell Biology. Memory, the ability of an animal after a first antigenic exposure to give a heightened and faster immune response upon a second exposure to the same antigen, is shown to be a property of bone marrow-derived cell lines. Expression of this memory depends on interaction with thymus-derived cells from either non-immunized or immunized mice. Chronic allotype suppression is described for the first time. It is initiated by in utero or neonatal exposure of (SJL x BALB/c)F, mice, allotype a/b, to anti b antibody. Suppression lasts for long periods and continues in irradiated recipients which have received lymphoid cells from suppressed donors. Selection against b allotype producing cell precursors can explain suppression.

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Diminution of β-Glucuronidase Activity in Post-Heparin Human Sera

Cited by 7 publications

References 6 publications

Some side effects of heparin, heparinoids, and their antagonists

Some side effects of heparin, heparinoids, and their antagonists

Beta‐glucuronidases: Their Significance and Relation to Cancer*

From cell biology to immunology—A short trip

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