The purpose of this study is to examine the relationship between self-handicapping and spiritual well-being. A total of 201 students, of which 121 males and 80 females studying in the Faculty of Theology of Akdeniz University participated in this study. Participants were found to have the lowest age of 20, the highest age of 40, and the average age of 22,35. In the survey; Spiritual Well-Being Scale developed by Ekşi and Kardaş (2017) and Self-Sabotage Scale, developed by Jones and Rohodewalt (1982) and adapted to Turkish language by Akın (2012) were used. The data obtained in the study was analyzed using SPSS (Statistical Package for Social Sciences) program for Windows 21.0. Whilst evaluation of data, descriptive statistics T-Test and Anova were conducted. The relationship between the dependent and independent variables of the survey was tested by Pearson correlation and the effect was tested by regression analysis. The findings were evaluated at the level of 5% significance in the 95% confidence interval (p <0.05). According to findings; there was no significant difference among the sexes.There was a significant positive correlation between Anomie and self-handicapping.Again, in the regression analysis made with the aim of determining the independent predictors of selfhandicapping, it has been found that Anomie predicts to prevent self-handicapping. Anatolian culture, which is spiritual oriented has many values that prevent self-handicapping. Rational, emotional and spiritual studies can offer both preventative and restorative contributions to prevent self-handicapping. It may be useful to structure the education of theology to include functional understanding of religion as well as understanding of essential religion.