Diode laser endoscopic cyclophotocoagulation in the normal equine eye

Abstract

Diode ECP between 0.90 and 1.14 J is a potential treatment option for glaucoma in horses based on visible tissue effects and target ciliary epithelium damage. Iatrogenic cataract development may limit the use of an anterior chamber approach in phakic horses. Supported in part by an ACVO VAF grant.

Equine glaucoma: Where are we now?

“…Although ECP effectively caused ciliary epithelium damage in one study with normal horses, iatrogenic cataract development may limit its use (Harrington et al . ). In addition, ECP requires general anaesthesia while TSCP may be performed in standing horses with sedation.…”

“…Rather than delivering laser energy from the outside of the globe through the sclera, as in TSCP, ECP combines an intraocular camera with a laser which allows visualisation of the ciliary processes and precise targeting during the laser ablation. Although ECP effectively caused ciliary epithelium damage in one study with normal horses, iatrogenic cataract development may limit its use (Harrington et al 2013). In addition, ECP requires general anaesthesia while TSCP may be performed in standing horses with sedation.…”

High intensity focused ultrasound cyclocoagulation in dogs with primary glaucoma: a preliminary study

“…Structural abnormality of the conventional outflow pathway comprising the pectinate ligament, the uveal and corneoscleral trabecular meshworks and the ciliary cleft (Read et al, 1998;Wood et al, 1998;Bjerkas et al, 2002;Kato et al, 2006;Strom et al, 2011;Plummer et al, 2013;Fricker et al, 2016;Bedford, 2017), or an abnormal biochemical metabolism of the trabecular meshworks (Hassel et al, 2007;Weinstein et al, 2007;Mackay et al, 2008aMackay et al, , 2008b), may be responsible for PG. Many surgical techniques have been described to manage PG, acting either on the production (De Roetth, 1965;Brightman et al, 1982;Hardman and Stanley, 2001;Lutz and Sapienza, 2009a;Azoulay et al, 2011;Harrington et al, 2013) or the egress of aqueous humor (Cullen et al, 1998;Cullen, 2004), or both at the same time (Sapienza and van der Woerdt, 2005;Lutz and Sapienza, 2009b;Amagai et al, 2014). Cyclocryothermy (De Roetth, 1965;Brightman et al, 1982), transscleral cyclophotocoagulations (TSCP) (Hardman and Stanley, 2001;Sapienza and van der Woerdt, 2005;Amagai et al, 2014) and endocyclophotocoagulation (ECP) (Lutz and Sapienza, 2009a,b;Azoulay et al, 2011;Harrington et al, 2013) http://www.openveterinaryjournal.com P.F.…”

“…Many surgical techniques have been described to manage PG, acting either on the production (De Roetth, 1965;Brightman et al, 1982;Hardman and Stanley, 2001;Lutz and Sapienza, 2009a;Azoulay et al, 2011;Harrington et al, 2013) or the egress of aqueous humor (Cullen et al, 1998;Cullen, 2004), or both at the same time (Sapienza and van der Woerdt, 2005;Lutz and Sapienza, 2009b;Amagai et al, 2014). Cyclocryothermy (De Roetth, 1965;Brightman et al, 1982), transscleral cyclophotocoagulations (TSCP) (Hardman and Stanley, 2001;Sapienza and van der Woerdt, 2005;Amagai et al, 2014) and endocyclophotocoagulation (ECP) (Lutz and Sapienza, 2009a,b;Azoulay et al, 2011;Harrington et al, 2013) http://www.openveterinaryjournal.com P.F. Isard et al Open Veterinary Journal, (2018), Vol.…”

“…Although the duration of effect on the normalization of the IOP remains variable with these techniques, TSLCP remains widely used in the management of PG. ECP is a more recent technique which aims to selectively destroy the ciliary processes via an intraocular approach (Lutz and Sapienza, 2009a,b;Azoulay et al, 2011;Harrington et al, 2013). Although it requires further studies to implement standardized procedures, ECP seems a promising surgery.…”