We report a high-efficiency Nd:LuVO 4 laser operating at 1066 and 1343 nm, respectively, direct pumped by a diode laser at 880 nm. The maximum outputs of 10.5 and 7.0 W, at 1066 and 1343 nm, respectively, are obtained in a 8-mm-thick 0.4 at.% Nd:LuVO4 crystal with 16.9 W of absorbed pump power at 880 nm, leading to a high slope efficiency with respect to the absorbed pump power of 64.4 and 44.5%. Under traditional pumping at 809 nm, the maximum outputs of 9.8 and 6.2 W, at 1066 and 1343 nm respectively, are obtained with 19.3 W of absorbed pump power, corresponding to the slope efficiency with respect to the absorbed pump power of 54.9 and 34.9%.