Diplonemid Glyceraldehyde-3-PhosphateDehydrogenase (GAPDH) and Prokaryote-to-Eukaryote Lateral Gene Transfer

Qian, Qing; Keeling, Patrick J.

doi:10.1078/1434-4610-00059

Cited by 31 publications

(26 citation statements)

References 31 publications

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“…In support of this hypothesis, dinoflagellates emerge from within the Heterokonta on the GAPDH tree obtained by Takishita et al (2004), making this tree compatible with the results generated by Yoon et al (2005). In fact, there is growing evidence that GAPDH genes themselves have been subject to lateral transfer (both plastidic and cytosolic forms) during protist evolution, including in dinoflagellates (Figge & Cerff, 2001;Qian & Keeling, 2001;Fagan & Hastings, 2002;Takishita et al, 2003Takishita et al, , 2004.…”

Section: Apicomplexan Plastid and Stability Of Plastid Envelopessupporting

confidence: 69%

Did the peridinin plastid evolve through tertiary endosymbiosis? A hypothesis

Bodył

Moszczyński

2006

European Journal of Phycology

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Most photosynthetic dinoflagellates harbour the peridinin plastid. This plastid is surrounded by three membranes and its characteristic pigments are chlorophyll c and the carotenoid peridinin. The evolutionary origin of this peculiar plastid remains controversial and is hotly debated. On the recently published tree of concatenated plastid-encoded proteins, dinoflagellates emerge from within the Chromista (clade containing cryptophytes, heterokonts, and haptophytes) and cluster specifically with Heterokonta. These data inspired a new version of the 'chromalveolate' model, according to which the peridinin plastid evolved by 'descent with modification' from a heterokont-like plastid that had been acquired from a rhodophyte by an ancestral chromalveolate. However, this model of plastid evolution encounters serious obstacles. Firstly, the heterokont plastid is surrounded by four membranes, which means that the ancestral peridinin plastid must have lost one of these primary membranes. However, such a loss could be traumatic, because it could potentially disturb protein import into and/or within the plastid. Secondly, on the phylogenetic tree of Dinoflagellata and Heterokonta, the first to diverge are not plastid, but heterotrophic, aplastidal taxa. Thus, when accepting the single origin of the heterokont and peridinin plastids, we would have to postulate multiple plastid losses, but such a scenario is highly doubtful when the numerous non-photosynthetic functions of plastids and their existence in heterotrophic protists, including parasitic lineages, are considered. Taking these obstacles into account, we suggest an alternative interpretation of the concatenated tree of plastid-encoded proteins. According to our hypothesis, the peridinin plastid evolved from a heterokont alga through tertiary endosymbiosis.

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Section: Apicomplexan Plastid and Stability Of Plastid Envelopessupporting

confidence: 69%

Did the peridinin plastid evolve through tertiary endosymbiosis? A hypothesis

Bodył

Moszczyński

2006

European Journal of Phycology

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“…Two intradomain and a putative interdomain prokaryotic LGT event were inferred, while two archaea-to-eukaryote transfers, two eukaryote-to-eukaryote and two putative eubacteria-to-eukaryote transfers were inferred from the phylogenetic analyses, all affecting phagotrophic eukaryotes [65]. Similar conclusions may be drawn from inspections of phylogenetic analyses of metabolic enzymes, such as GAPDH [55][56][57][58] and alcohol dehydrogenase ( fig. 2).…”

Section: Inter-or Intradomain Transfers?mentioning

confidence: 85%

“…There are additional hints that genes may be transferred between eukaryotes independent of endosymbioses. Phylogenetic analyses of the glyceraldehyde-3-phosphate (GAPDH) genes have revealed a very complex pattern of relationships which only can be explained by frequent gene transfers among and between prokaryotes and eukaryotes [55][56][57][58]. Interestingly, different lineages of dinoflagellates have acquired genes from euglenozoan lineages two, or maybe three, times independently [57].…”

Section: Gene Transfers Between Eukaryotes Independent Of Secondary Ementioning

confidence: 98%

Lateral gene transfer in eukaryotes

Andersson

2005

CMLS, Cell. Mol. Life Sci.

361

289

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Lateral gene transfer -- the transfer of genetic material between species -- has been acknowledged as a major mechanism in prokaryotic genome evolution for some time. Recently accumulating data indicate that the process also occurs in the evolution of eukaryotic genomes. However, there are large rate variations between groups of eukaryotes; animals and fungi seem to be largely unaffected, with a few exceptions, while lateral gene transfer frequently occurs in protists with phagotrophic lifestyles, possibly with rates comparable to prokaryotic organisms. Gene transfers often facilitate the acquisition of functions encoded in prokaryotic genomes by eukaryotic organisms, which may enable them to colonize new environments. Transfers between eukaryotes also occur, mainly into larger phagotrophic eukaryotes that ingest eukaryotic cells, but also between plant lineages. These findings have implications for eukaryotic genomic research in general, and studies of the origin and phylogeny of eukaryotes in particular.

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“…in the investigation of lateral gene transfer from prokaryote to eukaryote [21] , the location of PsGAPDH in protein phylogeny tree was likely to tell the kindred relation between P. sojae and diatom. Secondly, PsGAPDH's entry enlarges the C-II branch of subfamily GapC, implicating its cytosolic orientation.…”

Section: Discussionmentioning

confidence: 98%

“…As discussed previously, GAPDH was involved in compartment-specification [14] and recently used as a mark for lateral gene transfer [21] . Thus, homologues were divided into two distinct classes among diplonemid, called subfamilies Gap1-GapC (related to the cytosolic gapC of eukaryotes) and Gap2-GapA/B (related to cyanobacterial and proteobacterial gap3), respectively, showing differential intracellular locations and functions.…”

Section: Cloning and Sequence Analysis Of Psgapdhmentioning

confidence: 99%

A Phytophthora sojae gene of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induced in host infection and its anti-oxidative function in yeast

2006

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Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional protein well defined in eukaryotes, especially in mammalian and Saccharomyces cerevisiae. Using the method of suppression subtractive hybridization (SSH), we identified a Phytophthora sojae cDNA coding GAPDH, which was up-regulated during the early stage of soybean infection. The termed PsGapdh gene possessed three copies in the P. sojae genome. Its amino acid sequence harbored overall conserved domain of GADPH, homologous closest to GapC1 of Achlya bisexualis (oomycete) and adjoined to GapC2s of Odontella sinensis and Phaeodactylum tricornutum (diatom), on the C-branch of subfamily Ⅱ GapC in phylogeny tree of GAPDH. The transcriptional level of PsGapdh was up-regulated throughout early infection. Heterogenous expression of PsGapdh in the yeast tdh1-deleted mutant could rescue growth arrest under continuous exposure to H 2 O 2 . These results indicated active roles of PsGapdh in pathogen-host interaction and anti-oxidation.

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Diplonemid Glyceraldehyde-3-PhosphateDehydrogenase (GAPDH) and Prokaryote-to-Eukaryote Lateral Gene Transfer

Cited by 31 publications

References 31 publications

Did the peridinin plastid evolve through tertiary endosymbiosis? A hypothesis

Did the peridinin plastid evolve through tertiary endosymbiosis? A hypothesis

Lateral gene transfer in eukaryotes

A Phytophthora sojae gene of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induced in host infection and its anti-oxidative function in yeast

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