Diplopia Related to a Pediatric Cervical Rhabdoid Tumor in 18F-FDG PET

Abstract

Increased muscle uptake is commonly seen with 18 F-FDG PET/ CT because of an important physiological muscle glucose metabolism. Muscle uptake can express a recent significant muscle activity. However, the absence of muscle uptake is almost never described or interpreted. We describe the case of an 8-year-old boy with extrarenal rhabdoid tumor in the right carotid space. An MRI and an 18 F-FDG PET/CT were performed for the diagnostic workup. There was no uptake in the lateral rectus oculomotor muscle unlike all other oculomotor muscles. The ophthalmological examination found a diplopia confirmed by the Lancaster test.

Hypopituitarism due to a Large Osteoclastoma Arising from the Sphenoid Bone Invading the Pituitary Fossa in a Patient with Parathyroid Carcinoma

“…With parathyroidectomy and improvement of hyperparathyroidism, bone lesions tend to regress [9][10][11][12]. Tey can be found in any bone sites of the skeleton, being most commonly found in ribs, clavicles, spine, skull, and hip long bones [9,11,12]. However, atypical locations such as the sellar and parasellar region and sphenoid bone have been reported previously in one case [13], but without pituitary involvement.…”

“…It characteristically presents with severe bone involvement such as salt and pepper lesions in the skull, subperiosteal bone resorption, distal clavicle tapering, bone cysts, and brown tumors, also known as osteoclastomas [9,10]. Brown tumors are described as cystic lesions with a lithic aspect, benign, uni-or multifocal, flled with fbrotic tissue and granulation, typically with giant cells and other fusiform cells, containing hemorrhagic foci that allow the formation of hemosiderin deposits, leading to a brown coloration [10][11][12]. Brown tumors may manifest causing edema, bone pain, and spinal fracture.…”

“…In these cases, to confrm whether the lesion is secondary to hyperparathyroidism, biochemical examination is required, in which the increase in serum calcium level may occur in association with the increase in PTH. With parathyroidectomy and improvement of hyperparathyroidism, bone lesions tend to regress [9][10][11][12]. Tey can be found in any bone sites of the skeleton, being most commonly found in ribs, clavicles, spine, skull, and hip long bones [9,11,12].…”

Complimentary Role of [18F]FDG and [18F]NaF-PET/CT in Evaluating Synchronous Thyroid Carcinoma and Parathyroid Adenoma with Brown Tumors

“…Brown tumor (BT) is a benign, reactive skeletal manifestation of long-standing hyperparathyroidism. 1 BT can affect any bone and radiologic findings are nonspecific, leading to misinterpretation. 2 Although the guidelines do not consider hyperparathyroidism a risk factor for thyroid carcinoma, it is not uncommon among hyperparathyroidism patients.…”

FDG PET/CT Findings of Malignant Rhabdoid Tumor Arising From a Renal Allograft

“…The presence of subcapsular fluid collection, multilobulated architecture, and calcifications may suggest a malignant rhabdoid tumor of the kidney 5–9 . A limited number of case reports demonstrate that malignant rhabdoid tumor may show intense 10–14 or low-grade 15–18 FDG uptake. FDG PET/CT findings of renal malignant rhabdoid tumor have been rarely reported 12 .…”