Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Khunnawutmanotham, Nisachon; Chimnoi, Nitirat; Thitithanyanont, Arunee; Saparpakorn, Patchreenart; Choowongkomon, Kiattawee; Pungpo, Pornpan; Hannongbua, Supa; Techasakul, Supanna

doi:10.3762/bjoc.5.36

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Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Abstract: SummaryTen dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT.

Cited by 3 publications

References 11 publications

Phytochemistry and polypharmacology of cleome species: A comprehensive Ethnopharmacological review of the medicinal plants

Phytochemistry and polypharmacology of cleome species: A comprehensive Ethnopharmacological review of the medicinal plants

Simple and rapid determination of the enzyme kinetics of HIV-1 reverse transcriptase and anti-HIV-1 agents by a fluorescence based method

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