Direct analysis of continuous relaxation spectra

Deconvolution of Compartmental Water Diffusion Coefficients in Yeast-Cell Suspensions Using Combined T1 and Diffusion Measurements

“…3 and 4, respectively) employ numerical, continuous relaxography (8) to assay T 1 relaxation time differences in the compartmental signal contributions. That is, numerical ILT analysis (10)(11)(12) is used to calculate the continuous relaxation time distributions from a sample. A disadvantage of this approach is that the ILT method requires a measured value of M 0 for the sample, which results in long experiment times.…”

“…It employs relaxography (8,9), using a contrast reagent (CR) to distinguish between the IC and EC water proton signals based on differences in their respective longitudinal (T 1 ) relaxation times. This method is based on relaxography utilizing a numerical inverse Laplace transform (ILT) (10)(11)(12) of longitudinal relaxation data to produce a distribution of relaxation times that can be multimodal, depending on the number of populations in the sample. If this so-called "relaxogram" displays two distinct relaxation time peaks, a discrete ILT regression converges on the continuous distribution means.…”

Cell relaxation after electrodeformation: effect of latrunculin A on cytoskeletal actin

“…The problem is well known to be illposed and the solution is extremely sensitive to noise (Provencher and Dovi, 1979). A common strategy for solving the problem is to reduce the number of degrees of freedom (e.g.…”

Molecular-dynamics simulations of thin polyisoprene films confined between amorphous silica substrates

“…Overall, the segmental relaxation in all film layers is shifted to larger times with decreasing the PI film thickness. The orientational segmental relaxation has been analyzed further using the CONTIN 75,[93][94][95] method. The normalized distribution functions of segmental relaxation times…”