Direct and indirect impact on rotavirus positive and all-cause gastroenteritis hospitalisations in South Australian children following the introduction of rotavirus vaccination

Effect of pentavalent rotavirus vaccine introduction on hospital admissions for diarrhoea and rotavirus in children in Rwanda: a time-series analysis

“…Finally, indirect protection of children too old to have been vaccinated with rotavirus vaccine has been previously reported in several high-income and middleincome countries including the USA, Australia, Austria, and El Salvador. 23,24,26,[55][56][57][58] We provide the fi rst possible evidence of indirect protection from rotavirus vaccination in a high-burden, low-income setting. This study has some limitations.…”

Trends in severe gastroenteritis among young children according to socio-economic characteristics before and after implementation of a rotavirus vaccination program in Quebec

“…This reduction corresponds to that observed in many studies in industrialized countries, ranging from 30% to 60%. [9][10][11][18][19][20][21] However, our study went further than previous studies by examining these trends according to several individual-and neighbourhood-level characteristics. As expected, children less than three years, who were eligible to receive the funded rotavirus vaccine, had the highest reductions, suggesting that the observed decline in gastroenteritis hospitalizations was due to rotavirus vaccine.…”

“…Although it did not reach statistical significance, this observation suggests a herd immunity effect of the vaccine, also observed in many other studies. [18][19][20][21] Children living in Sherbrooke, which is the most central and most populous city, as well as those living in the densest DAs, had the lowest reductions in AGE hospitalization rates in comparison with children living in more rural areas. Urban clusters with high population density could increase the potential for transmission of rotavirus or other gastrointestinal pathogens, explaining the lower reduction in AGE hospitalizations in urban areas despite high vaccine coverage.…”

Evaluation of the Cost-Effectiveness of Vaccination of Children with 5-valent Vaccine against Rotavirus Infection in the Russian Federation

“…популяционного эффекта, то в Финляндии, где массовая вакцинация против РВИ была начата в 2009 г., а охват вакцинацией составил 95-97%, было выявлено снижение частоты госпитализации по поводу РВИ у детей старших возрастных групп, не подлежащих вакцина-ции, на 54-75%, а частоты амбулаторных посещений по поводу РВИ -на 30-79% [17]. Развитие популяцион-ного эффекта после начала массовой вакцинации про-тив РВИ было продемонстрировано также в Австрии, Бельгии, Великобритании и ряде других стран [18][19][20][21][22][23].…”