Diseases of the circulatory system are one of the main causes of death and disability in the population. The high prevalence of conditions associ-ated with heart rhythm disturbances is due to associated conditions and concomitant diseases, and this cohort of persons, as a rule, is on lifelong pharmacotherapy. In accordance with clinical guidelines, anticoagulant therapy is indicated for patients with heart rhythm disturbances, which can often pose a risk of microcirculation disturbance. Inflammatory processes in the oral cavity lead to endothelial dysfunction and microcirculation disorders, which is one of the predictors in the development of hypertension, which is associated with rhythm disturbances.Due to the possibility of developing microcirculation disorders and the risk of bleeding, it is important for a dentist to understand the features of the management and treatment of these patients, as well as approaches to the prevention of exacerbations of dental diseases.