Direct electrochemistry of horseradish peroxidase based on biocompatible carboxymethyl chitosan–gold nanoparticle nanocomposite

Green Synthesis, Cytotoxicity and Utilization of Carboxymethylchitosan-Stabilized Gold Nanoparticles.

“…Amino groups have been used as metal nanoparticles stabilizer [14,22]. So that we suggest that free amino groups in O-CMCS could bind with gold nanoparticles to stabilize it.…”

“…So that we suggest that free amino groups in O-CMCS could bind with gold nanoparticles to stabilize it. When chitosan used instead of O-CMCS to stabilize AuNPs aggregation of nanoparticles occurs due to chitosan insoluble in both neutral and alkaline medium [11,14]. Figure 2 shows TEM images of the O-CMCS-AuNPs nanocomposites.…”

“…Unlike most gold colloid, few amount of nonspherical particles beside most spherical one was observed. These non-spherical particles seemed to be fabricated by gathered interference of two or three spherical particles during the nucleation process [14,23]. Spectrophotometry is another important aspect for characterization of gold nanoparticles.…”

“…high viscosity, biodegradability, biocompatibility and low cytotoxicity. Herein chemical modification perform only on OH groups to form OCH 2 COOH, which retain NH 2 groups accessible for reaction i.e., O-CMCS has both COOH and NH 2 groups used to stabilize AuNPs so that O-CMCS used as capping agent as well as reducing agent [14].…”

Electrochemical Determination of Nitrite and Iodate Based on Pt Nanoparticles Self-assembled on a Chitosan Modified Glassy Carbon Electrode

“…It has already been described as a promising material for modification of the electrode surface, due to its attractive properties, such as excellent film-forming ability, good stability, high permeability toward water, strong adherence to the electrode surface, biocompatibility, no toxicity, high mechanical strength and susceptibility to chemical modifications due to the presence of reactive amino and hydroxyl functional groups from its structure. 11,12 Many studies have reported on the ability of chitosan to bind with metal ions and the support metal nanoparticles, [13][14][15][16][17][18][19][20][21][22][23] and several electrochemical sensors have been developed based on the interaction between chitosan and analytes. [24][25][26][27][28][29][30] However, we have not found any papers concerning the detection of iodate using a chitosan-modified electrode.…”