Direct enantioselective α-alkylation of secondary acyclic amines with ketones by combining photocatalysis and lipase catalytic promiscuity

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Direct enantioselective α-alkylation of secondary acyclic amines with ketones by combining photocatalysis and lipase catalytic promiscuity

Abstract: A novel direct enantioselective α-alkylation of secondary acyclic amines with simple ketones by combining photocatalysis and lipase catalytic promiscuity is described. Various β-amino ketones were synthesized from secondary acyclic amines...

Cited by 4 publications

References 54 publications

Efficient stereoselective synthesis of aryl lactones using engineered ketoreductase ChKRED20 from Chryseobacterium sp. CA49

Efficient stereoselective synthesis of aryl lactones using engineered ketoreductase ChKRED20 from Chryseobacterium sp. CA49

Development of a photoenzymatic one-pot hybrid system for the direct synthesis of 3,3-disubstituted indole-2-ketones from N-methyl indoles

Recent advances in catalytic asymmetric condensation reactions for the synthesis of nitrogen containing compounds

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