Direct Endovascular Thrombolytic Therapy for Dural Sinus Thrombosis

Kim, S Y; Suh, Jung Ho

doi:10.1097/00041327-199906000-00042

Cited by 50 publications

(82 citation statements)

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“…Complications from thrombolytic treatment included extracranial hemorrhage, intracranial hemorrhage. Recanalization occurred in most patients and was less likely to occur in those patients treated with systemic thrombolytics [39,[41][42][43][44]. Based on these studies, thrombolytics may benefit some patients for which anticoagulation therapy does not prove sufficient treatment.…”

Section: Thrombolyticsmentioning

confidence: 93%

Two cases of venous sinus thrombosis in women taking the oral contraceptive pill, Yaz (dropirenone/ ethinyl estradiol), and review of the literature

Riordan¹,

Deshaies²

2013

Health

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Cerebral venous sinus thrombosis (CVT) is a rare cause of stroke and the clinical presentation is variable, thus mimicking other neurologic pathologies. One of the more common acquired risk factors of venous sinus thrombosis is oral contraceptive medications such as Yaz. While the prognosis for CVT is favorable, it is important to identify and treat early to prevent neurologic deficits. We report two cases of young female patients who presented with sinus thrombosis and review the current literature on this topic. CVT accounts for 0.5% of strokes and most commonly presents with headaches and in many cases focal neurologic deficits. Diagnosis is confirmed with neuroimaging including CT angiography or MR angiography. Treatment consists of anticoagulation and in some cases, thrombolytic therapy is beneficial. The overall prognosis of CVT is favorable but, further research is needed to outline optimal treatment options including the duration of anticoagulation therapy and the role of thrombolytic therapy to prevent serious neurologic deficits.

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Section: Thrombolyticsmentioning

confidence: 93%

Two cases of venous sinus thrombosis in women taking the oral contraceptive pill, Yaz (dropirenone/ ethinyl estradiol), and review of the literature

Riordan¹,

Deshaies²

2013

Health

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show abstract

“…28,[32][33][34] Since our patient, Tsai et al 36 reported on a series of 25 patients; 8 patients (6 with hemorrhage on initial CT) were treated with thrombectomy and a total rt-PA dose that ranged from 3 to 10 mg infused at 1 mg/minute. Five patients had symptomfree recovery and three had mild residual weakness.…”

Section: Surgerymentioning

confidence: 99%

“…4,29 Surgical management may include decompressive craniectomy, endovascular intervention with locally infused rt-PA, or mechanical thrombolysis using microwires or available commercial devices. 5,[30][31][32][33] Information in the literature provides little guidance regarding optimum dosing of endovascularly-administered thrombolytic therapy for cranial sinus thrombosis. Significant variability also exists in patient selection for interventional management of cranial sinus thrombosis and the ideal thrombolytic agent and dosage.…”

Section: Treatmentmentioning

confidence: 99%

Intracranial Dural Sinus Thrombosis: Novel Use of a Mechanical Thrombectomy Catheter and Review of Management Strategies

Khan

Adeoye²,

Abruzzo

et al. 2009

Clinical Medicine & Research

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“…Kim and Suh described 9 patients, 1 of whom had pretreatment hemorrhage that remained stable. 12 Kumar et al described 19 patients, and 2 of these patients showed fatal worsening of hemorrhages after thrombolysis. 13 There is currently no evidence from randomized controlled trials about the efficacy and safety of either systemic or local thrombolytic therapy in patients with cerebral venous and sinus thrombosis.…”

Section: Figmentioning

confidence: 99%