Direct evidence of histopathological impacts of wastewater discharge on resident Antarctic fish ( Trematomus bernacchii ) at Davis Station, East Antarctica

Corbett, Patricia A.; King, Catherine K.; Stark, Jonathan S.; Mondon, Julie

doi:10.1016/j.marpolbul.2014.08.012

Cited by 20 publications

(10 citation statements)

References 52 publications

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“…Now it is well documented that concentrations of environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs) are increasing in the Southern Ocean. Antarctic biota, such as fish, are accumulating the xenobiotics in their fat‐rich tissues . To date, the biological and physiological response of Antarctic fish to increasing toxicant body burdens is largely unknown.…”

Section: Introductionmentioning

confidence: 99%

Expression of aryl hydrocarbon receptor–regulated genes and superoxide dismutase in the Antarctic eelpout Pachycara brachycephalum exposed to benzo[a]pyrene

Strobel

Mark

Segner

et al. 2018

Enviro Toxic and Chemistry

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The aryl hydrocarbon receptor (AhR) pathway mediates many, if not all, responses of fish to dioxin-like compounds. The Southern Ocean is progressively exposed to increasing concentrations of anthropogenic pollutants. Antarctic fish are known to accumulate those pollutants, yet nothing is known about their capability to induce chemical biotransformation via the AhR pathway. The objective of the present study was to investigate whether Antarctic eelpout, Pachycara brachycephalum, respond to anthropogenic pollutants by activation of the AhR and its target gene cytochrome P4501A (CYP1A), and of superoxide dismutase (SOD), which served as a representative for oxidative stress. We exposed P. brachycephalum to 10 and 100 mg benzo[a]pyrene (BaP)/kg body weight for 10 d and measured the expression of AhR, CYP1A, and SOD in liver tissue via quantitative polymerase chain reaction. We identified two distinct AhR isoforms in the liver of P. brachycephalum. Antarctic eelpout responded to both BaP exposures by an up-regulation of AhR and SOD, and by a particularly strong induction of CYP1A expression, which remained high until day 10 of the exposure time. Our data suggest that P. brachycephalum possesses the potential to up-regulate xenobiotic biotransformation pathways, at least at the gene expression level. The time course of the AhR and CYP1A response points to an efficient but slow xenobiotics metabolism. Moreover, BaP exposure could include adverse effects such as oxidative stress. Environ Toxicol Chem 2018;37:1487-1495. © 2018 SETAC.

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Section: Introductionmentioning

confidence: 99%

Expression of aryl hydrocarbon receptor–regulated genes and superoxide dismutase in the Antarctic eelpout Pachycara brachycephalum exposed to benzo[a]pyrene

Strobel

Mark

Segner

et al. 2018

Enviro Toxic and Chemistry

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“…Pressures from pollution were assessed using global models for chemical pollutants, nutrients and trash and local models for pathogen pollution, where the only major source of pathogens to Antarctic waters is from scientific research bases and ships (Tin et al, 2009;Martins et al, 2012;Corbett et al, 2014Corbett et al, , 2015Emnet et al, 2015). The volume of wastewater inputs and pathogen contamination in the Antarctic is small relative to many more populated coastal ocean regions.…”

Section: Discussion Understanding Scores In the Context Of Antarcticamentioning

confidence: 99%

“…Some data are available indicating elevated pathogen levels and other contaminants near some Antarctic bases (Tin et al, 2009) and near wastewater outfalls (Martins et al, 2012;Corbett et al, 2014Corbett et al, , 2015Emnet et al, 2015). ATS regulations require stations with more than 30 residents to treat wastewater.…”

Section: Clean Watersmentioning

confidence: 99%

Using the Ocean Health Index to Identify Opportunities and Challenges to Improving Southern Ocean Ecosystem Health

et al. 2017

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“…Despite their impact on productivity and economy, when misused, these agents can contaminate soil and water (Li 2018;Woodrow et al 2018). Since most formulations still applied in crops are not speci c for pests, their compounds can directly or indirectly affect the structure and biological function of non-target organisms, such as amphibians and shes (Annett et al 2014;Corbett et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Combinatorial Effects of Organophosphate (Temephos), Glyphosate (Roundup) and Sodium Dodecil Sulfate (Sds) on Zebrafish (Danio Rerio) Gills: A Morphometric and Histological Study

Santos-Silva¹,

Ribeiro²,

Alves³

et al. 2021

Preprint

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Pesticides, as Temephos and Roundup, and surfactants, like Sodium Dodecyl Sulfate (SDS), when dicharged into the environment, are harmful to non-target wildlife, especially fish. To evaluate the effects of those chemicals alone and their binary combinations, we assessed the histological alterations in Danio rerio gills after 15 days of exposure to Temephos (1ppm), Roundup (10ppm), SDS (2ppm), SDS plus Temephos (2ppm+1ppm), SDS plus Roundup (2ppm+10ppm) and Temephos plus Roundup (1ppm+10ppm). Hyperplasia, a regressive change, was significant in all exposed groups. The progressive change, complete fusion of lamellae, was significantly intensive in Roundup plus Temephos group. Regarding to circulatory disturbances, vascular congestion was significant intensive in SDS group, while severe aneurysm was observed in Roundup group. Although xenobiotics in the blend are biologically complex, mainly for long periods, combinatorial exposure incremented only complete lamellar fusion. Our results reinforce the rationalization of indiscriminate use of those compounds alone or in combination.

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Direct evidence of histopathological impacts of wastewater discharge on resident Antarctic fish ( Trematomus bernacchii ) at Davis Station, East Antarctica

Cited by 20 publications

References 52 publications

Expression of aryl hydrocarbon receptor–regulated genes and superoxide dismutase in the Antarctic eelpout Pachycara brachycephalum exposed to benzo[a]pyrene

Expression of aryl hydrocarbon receptor–regulated genes and superoxide dismutase in the Antarctic eelpout Pachycara brachycephalum exposed to benzo[a]pyrene

Using the Ocean Health Index to Identify Opportunities and Challenges to Improving Southern Ocean Ecosystem Health

Combinatorial Effects of Organophosphate (Temephos), Glyphosate (Roundup) and Sodium Dodecil Sulfate (Sds) on Zebrafish (Danio Rerio) Gills: A Morphometric and Histological Study

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