“…Moreover, emerging environmentally responsive materials can find their applications in biosensing and bio-manipulation platforms 127Table 1Materials used in the desktop micro-nanofabricationMaterial categories | Representative materials | Typical micro-nanofabrication methods | Biocompatibility and toxicity | Biomedical applications |
Thermoset polymers | PDMS6,49,53,62,116,126,156,177,201,204,216,217 | Molding | Biocompatible | Used in almost all microfluidic and bio-/nanopatterning applications |
Thermoplastic polymers | PMMA102,115 | Hot embossing | Biocompatible | Construct for microfluidics |
COC172 | Hot embossing | Biocompatible | Used in optofluidic applications primarily |
Polystyrene/polyolefin28,59,137,171 | Heat-activated shrinkage | Biocompatible | Device packaging; pattern transfer; cell culture platform |
Photopatternable polymers | SU81,18,23,45,113 KMPR170 | Lithography | Toxic | Master for microfluidics and bio/nanopatterning |
Dry film79,105,173,183,184,192,193,214 | Lithography | Biocompatible | Master for microfluidics and bio/nanopatterning |
PEG38,100,104,159,160 | |
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