Direct Fluoroalkylthiolation Based on Fluoroalkanesulfite Derivatives

Abstract

Fluoroalkylthio groups have received substantial attention in the past decade because of their unique physicochemical characteristics, and methods for incorporating these substituents into organic molecules have been rapidly developed in recent years. This account summarizes our efforts on the development of direct fluoroalkylthiolation with fluoroalkanesulfite derivatives, several innovative and efficient strategies for the fluoroalkylthiolation of various substrates have been disclosed, affording various valuable fluoroalkylthiolated compounds in good yields.