Direct full compensation of the aberrations in quantitative phase microscopy of thin objects by a single digital hologram

Miccio, Lisa; Alfieri, Domenico; Grilli, Simonetta; Ferraro, Pietro; Fińizio, Andrea; Petrocellis, Luciano De; Nicola, Sergio De

doi:10.1063/1.2432287

Cited by 178 publications

(80 citation statements)

References 18 publications

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“…Aberrations or other deformations of wavefronts can easily be compensated by using a matching reference wave [22,50,51]. Multiwavelength optical phase unwrapping (see Sec.…”

Section: Comparisons Of Analog and Digital Holographic Microscopymentioning

confidence: 99%

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Principles and techniques of digital holographic microscopy

2010

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Abstract. Digital holography is an emerging field of new paradigm in general imaging applications. We present a review of a subset of the research and development activities in digital holography, with emphasis on microscopy techniques and applications. First, the basic results from the general theory of holography, based on the scalar diffraction theory, are summarized, and a general description of the digital holographic microscopy process is given, including quantitative phase microscopy. Several numerical diffraction methods are described and compared, and a number of representative configurations used in digital holography are described, including off-axis Fresnel, Fourier, image plane, in-line, Gabor, and phase-shifting digital holographies. Then we survey numerical techniques that give rise to unique capabilities of digital holography, including suppression of dc and twin image terms, pixel resolution control, optical phase unwrapping, aberration compensation, and others. A survey is also given of representative application areas, including biomedical microscopy, particle field holography, micrometrology, and holographic tomography, as well as some of the special techniques, such as holography of total internal reflection, optical scanning holography, digital interference holography, and heterodyne holography. The review is intended for students and new researchers interested in developing new techniques and exploring new applications of digital holography. C 2010 Society of Photo-Optical Instrumentation Engineers.

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“…Aberrations or other deformations of wavefronts can easily be compensated by using a matching reference wave [22,50,51]. Multiwavelength optical phase unwrapping (see Sec.…”

Section: Comparisons Of Analog and Digital Holographic Microscopymentioning

confidence: 99%

“…155, and in Ref. 50, the Zernike polynomial fit is used to subtract curvature and aberrations from the background of the DHM image. In Ref.…”

Section: Wavefront Compensationmentioning

confidence: 99%

Principles and techniques of digital holographic microscopy

2010

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“…Three-dimensional (3D) optical transfer function (OTF) for DHM is given in [56]. Numerical techniques are also available for addressing specific purposes such as dc and twin term removal [57][58][59] diffraction onto an inclined planes [51,60,61], automatic focus detection [62,63], two-step Fresnel diffraction method for pixel resolution control [64], and aberration compensation [65].…”

Section: Principles Of Digital Holographymentioning

confidence: 99%

Applications of Digital Holography in Biomedical Microscopy

Kim

2010

Journal of the Optical Society of Korea

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Digital holography (DH) is a potentially disruptive new technology for many areas of imaging science, especially in microscopy and metrology. DH offers a number of significant advantages such as the ability to acquire holograms rapidly, availability of complete amplitude and phase information of the optical field, and versatility of the interferometric and image processing techniques. This article provides a review of the digital holography, with an emphasis on its applications in biomedical microscopy. The quantitative phase microscopy by DH is described including some of the special techniques such as optical phase unwrapping and holography of total internal reflection. Tomographic imaging by digital interference holography (DIH) and related methods is described, as well as its applications in ophthalmic imaging and in biometry. Holographic manipulation and monitoring of cells and cellular components is another exciting new area of research. We discuss some of the current issues, trends, and potentials.

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“…Using a dual wavelength technique, it has been shown that sub-nanometer accuracy can be achieved 5 . An important advantage of DHM is that the aberrations resulting from imperfect optics can be completely compensated 6,7 . The digital holographic imaging system is a hybrid opto-digital system in which the wavefield from an object is captured on an image sensor by interference and processed numerically to extract the phase of the wavefield.…”

Section: Introductionmentioning

confidence: 99%