Fluid discrimination plays an important role in reservoir exploration and development. At present, the fluid factors used for fluid discrimination are estimated by linear AVA inversion methods based on the linear approximations of the Zoeppritz equations. However, the Zoeppritz equations show that the relationship between prestack AVA reflection coefficients and reservoir parameters is highly nonlinear. Therefore, inversion methods based on linear approximations will seriously influence the nonuniqueness and uncertainty of inversion results. In this paper, a nonlinear inversion based on the quadratic approximation is carried out to reduce the nonuniqueness and uncertainty of fluid factor. Firstly, in order to directly invert the fluid factor, a novel quadratic approximation in terms of the fluid factor (
ρ
f
), shear modulus, and density on both sides of the reflection interface is derived based on poroelasticity theory. Then, a nonlinear inversion objective function is constructed using the novel quadratic approximation in a Bayesian framework, and the Gauss-Newton method is adopted to minimize this objective function. The synthetic data example shows that the new method can obtain reasonable fluid factor inversion results even in low SNR (signal-to-noise ratio) case. Finally, the proposed method is also applied to field data which shows that it can effectively discriminate reservoir fluids.