Direct measurement of the interaction of model food emulsion droplets adhering by arrested coalescence

Frostad, John M.; Collins, Martha C.; Leal, L. Gary

doi:10.1016/j.colsurfa.2013.09.028

Cited by 12 publications

(5 citation statements)

References 18 publications

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“…Due to the higher stiffness of the capillaries, these have a force resolution of ~1 nN which is two orders of magnitude higher than MFS. Using CCFA, the interaction forces between vesicles [56] and food emulsion droplets [57] were investigated. Although MFS and CCFA are very similar, they differ in how the cantilevers are manufactured.…”

Section: Development Of the Approachmentioning

confidence: 99%

Micropipette force sensors for in vivo force measurements on single cells and multicellular microorganisms

Backholm

Bäumchen

2019

Nat Protoc

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Section: Development Of the Approachmentioning

confidence: 99%

Micropipette force sensors for in vivo force measurements on single cells and multicellular microorganisms

Backholm

Bäumchen

2019

Nat Protoc

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“…Partial coalescence can also be observed in o/w emulsions containing solid particles that are completely wetted by the oil. Frostad et al [ 105 ] measured the interaction forces between two solid-in-oil-droplets attached to two capillaries immersed in water. The magnitude of the forces measured between drops as they came into close contact were consistent with those predicted assuming that capillary bridges form between the drops [ 105 ].…”

Section: Coalescing Dropsmentioning

confidence: 99%

“…Frostad et al [ 105 ] measured the interaction forces between two solid-in-oil-droplets attached to two capillaries immersed in water. The magnitude of the forces measured between drops as they came into close contact were consistent with those predicted assuming that capillary bridges form between the drops [ 105 ]. Pawar et al [ 106 ] observed coalescence between partially crystalline oil droplets, as the elastic modulus of the oil was varied by altering the concentration of fat crystals in the drops.…”

Section: Coalescing Dropsmentioning

confidence: 99%

Controlling Pickering Emulsion Destabilisation: A Route to Fabricating New Materials by Phase Inversion

Whitby

Wanless

2016

Materials

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The aim of this paper is to review the key findings about how particle-stabilised (or Pickering) emulsions respond to stress and break down. Over the last ten years, new insights have been gained into how particles attached to droplet (and bubble) surfaces alter the destabilisation mechanisms in emulsions. The conditions under which chemical demulsifiers displace, or detach, particles from the interface were established. Mass transfer between drops and the continuous phase was shown to disrupt the layers of particles attached to drop surfaces. The criteria for causing coalescence by applying physical stress (shear or compression) to Pickering emulsions were characterised. These findings are being used to design the structures of materials formed by breaking Pickering emulsions.

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“…Stress relaxation data for sample #2 are fitted to a stretched exponential model following Frostad et al [ 30 ] to determine the stretching exponent, β , and characteristic relaxation time,

t_{c}

, for the neurosphere. Note that, sequentially, the maximum in the force and in position decreases with subsequent compressions.…”

Section: Resultsmentioning

confidence: 99%

“…We characterized the mechanical properties of the neurospheres using the CCFA. [ 28,30–32 ] The device uses a cantilevered capillary (inner diameter or ID 50 μm, outer diameter or OD 360 μm) to aspirate and hold a single neurosphere within a reservoir of PBS. A second, rigid capillary (ID 5 μm, OD 360 μm) then compresses the neurosphere against the cantilevered capillary ( Figure ).…”

Section: Methodsmentioning

confidence: 99%

The Mechanical Properties of Neurospheres

Okwara

Ghaemi

et al. 2021

Adv Eng Mater

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Stem cell‐derived 3D tissues such as spheroids are excellent models for investigating mechanisms of tissue formation and responses to physiological and mechanical cues. Neuronal spheroids, also known as neurospheres, have attracted particular interest. A lot is now known about the differentiation and maturation of neurospheres, as well as their responses to biochemical cues. However, understanding about their mechanical properties pales in comparison, which is all the more galling in light of newfound insights about how mechanical stimuli trigger the onset of neurodegenerative conditions. Herein, formative steps are taken to fill this knowledge gap. Neurospheres are generated from murine neural stem cells and are subjected to compressive forces. It is observed that neurospheres exhibit stress relaxation under static compression and viscoelastic behavior at low strains. The suitability of the Tatara model for characterizing the mechanical properties of neurospheres is also evaluated. The study is the first study of its kind to investigate the mechanical properties of in vitro 3D tissues. Moreover, the methodologies developed in the study can also be used to improve the quality and safety of cell and tissue biomanufacturing processes.

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Direct measurement of the interaction of model food emulsion droplets adhering by arrested coalescence

Cited by 12 publications

References 18 publications

Micropipette force sensors for in vivo force measurements on single cells and multicellular microorganisms

Micropipette force sensors for in vivo force measurements on single cells and multicellular microorganisms

Controlling Pickering Emulsion Destabilisation: A Route to Fabricating New Materials by Phase Inversion

The Mechanical Properties of Neurospheres

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