Direct Mechanical Ventricular Actuation for Cardiac Arrest in Humans

Efficacy and Mechanisms of Biventricular and Left/Right Direct Cardiac Compression in Acute Heart Failure Sheep

“…While other DCC devices are in experimental (6–11) and clinical (12,13) use, these devices are not capable of both univentricular and BiV assists, making the results of the present study difficult to compare with others. From the present study, however, it can be concluded that BiV DCC is superior to that of LV or RV DCC alone, and that LV and RV assists contribute equally to the efficacy of BiV support.…”

An Artificial Myocardium Assist System: Electrohydraulic Ventricular Actuation Improves Myocardial Tissue Perfusion in Goats

“…28, No. 9,2004 committee at the Tohoku University. All goats were premedicated with atropine sulfate (0.4 mg IM).…”

Nonpharmacologic Management off Cardiac Arrest and Cardiogenic Shock

“…A recent feasibility study in patients with cardiac arrest demonstrated the average application took less than 2 min from the time of skin incision, and resulted in immediate hemodynamic improvement. 74 Anstadt et al 74 provided the following description of how the device works.…”

“…During actuation, the ventricular myocardium is 'pushed' into systole and 'pulled' into diastole configurations creating an action with remarkable effectiveness . .. 74 Although DMVA was initially described in the mid1960s, only a few studies in humans have been performed using this device. One report was a clinical feasibility trial demonstrating that in patients with prolonged cardiac arrest, unresponsive to traditional medical interventions, DMVA could be applied rapidly.74 In fact, in 22 patients in cardiac arrest for more than 40 min, the application of the device took less than 2 min from the time of skin incision.…”