“…Rather than using Kochi conditions, however, we set out to develop a metal- and light-free Giese method (conditions B), inspired by our recent success with metal- and light-free Minisci reactions. 18 Using DMSO as the solvent allows for the breakdown of S 2 O 8 2− V to the active SO 4 −· VI ( E ox = +2.51–3.1 V vs. SHE) 19 under mild conditions (40–50 °C), without the need for metal mediation or photolysis (Scheme 2). 18,20 This could potentially be exploited in the Giese reaction, since SET between VI and carboxylate I ( E ox = +1.17 V vs. SCE) 17,21 can then occur to give radical VII , 22 which should decarboxylate to give the carbamoyl radical II 9 a ,23 for the Giese addition with 8 .…”