We investigated and compared the turbulent characteristics of two-liquid mixing in single-orifice and multiorifice-impinging transverse (MOIT) jet mixers through large eddy simulations and the planar laser-induced fluorescence technique. Our focus is on evaluating the roles played by the interactions among the jets in the mixing intensification. The turbulent vortex structures, time-averaged mean concentration distributions, root-mean-square of the concentration fluctuations, probability density function, and power spectral density are discussed. For the MOIT jet mixer with large jet-to-crossflow velocity ratios, direct impingement of the jets enhances the mixing by speeding up the evolution of the counter-rotating vortex pairs, resulting in reduction in the vortex scale, increasing the vortex magnitude, and homogenizing the vortex distribution. The effect of the mixer scale-up on the turbulent characteristics was also studied. Moreover, we selected a specific MOIT jet mixer to perform optimization of the orifice number and diameter of the jet flow with fixed other parameters.