2021
DOI: 10.1101/2021.09.28.462247
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Direct quantification of ligand-induced lipid and protein microdomains with distinctive signaling properties

Abstract: Lipid rafts are known as highly ordered lipid domains that are enriched in saturated lipids such as the ganglioside GM1. While lipid rafts are believed to exist in cells and to serve as signaling platforms through their enrichment in signaling components, they have never been directly observed in the plasma membrane without treatments that artificially cluster GM1 into large lattices. Here we report that microscopic GM1-enriched domains can form, without lipid crosslinking, in the plasma membrane of live mamma… Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2023
2023
2023
2023

Publication Types

Select...
1

Relationship

1
0

Authors

Journals

citations
Cited by 1 publication
references
References 64 publications
(113 reference statements)
0
0
0
Order By: Relevance