Direct synthesis of thioethers from sulfonyl chlorides and activated alcohols

Recent Advances in Aryl Alkyl and Dialkyl Sulfide Synthesis

“…an efficient and practical method was developed for the synthesis of alkyl aryl sulfides via the treatment of aromatic sulfonyl chlorides with activated alcohols under nonaqueous condition (Scheme 23)[72].…”

Synthesis and structural characterization of a new self-assembled disulfide linked meso-tetrakis-porphyrin macromolecular array

“…Despite the existence in the literature of several methods of reduction of sulfonic acids and sulfonyl chlorides to the thiol and disulfide level, using a large variety of reagents [16][17][18][19][20][21][22][23][24], these methods were not exploited in porphyrin chemistry. We decided to follow the me thod of reduction of the sulfonyl chlorides to disulfides with the purpose of synthesizing new mesosulfur-containing tetrakis porphyrins.…”

Synthesis of Diversified Thioethers, 1-Aroylalkylisoquinolin-1-yl Thioethers, by Electrophilic S-Alkylation of 3-Phenyl Isoquinoline-1(2H)-thione

“…[4][5][6][7] Many syntheses have been reported for the preparation of thioethers. [8][9][10][11][12][13][14][15][16][17][18] Commonly employed methods are the alkylation of thiols. [19][20][21][22] Thioethers have been prepared by many methods; however, the synthetic scope is often hampered by use of expensive materials, high temperature, hazardous and corrosive compounds such as alkylating agents and strong reducing agents, harsh reaction conditions, and tedious workup procedures, resulting in low product yield.…”