Directly Measured Adherence to Treatment in Chronic Heart Failure: LEVEL-CHF Registry

Jelínek, Libor; Václavík, J.; Ramík, Zdeněk; Pavlů, Luděk; Benešová, Klára; Jarkovský, Jiří; Lazarová, Marie; Janečková, Hana; Spurná, Jana; Táborský, Miloš

doi:10.1016/j.amjms.2020.12.004

Cited by 8 publications

(11 citation statements)

References 29 publications

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“…Failure to identify poor medication adherence can promote needless intensification of therapy, which may adversely affect compliance due to the increased pill burden or regimen complexities. However, the available methods of assessing medication adherence in patients with HF are based on self-reported adherence measures subject to subjectivity [ 16 ]. As a result, the estimation of adherence in clinical practice correlates poorly with actual adherence due to recall bias and social desirability responses from interviewees, leading to an overestimation of actual adherence [ 13 , 16 ].…”

Section: Discussionmentioning

confidence: 99%

“…While objective methods are more robust than subjective methods, they are often expensive, burdensome to the healthcare provider, and may be impractical for routine clinical use [ 12 , 13 , 15 ]. Given these drawbacks, most available clinical and research data on medication adherence in patients with HF is based on subjective methods, primarily from the Western world [ 16 ]. Measurement of patient medication adherence is rare in Africa, where HF mortality remains high.…”

Section: Introductionmentioning

confidence: 99%

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Objectively measured medication adherence using assays for carvedilol and enalaprilat in patients with heart failure in Mozambique and Nigeria

Mwita,

Joubert,

Saidu

et al. 2023

International Journal of Cardiology Cardiovascular Risk and Pre

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Objectively measured medication adherence using assays for carvedilol and enalaprilat in patients with heart failure in Mozambique and Nigeria

Mwita,

Joubert,

Saidu

et al. 2023

International Journal of Cardiology Cardiovascular Risk and Pre

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“…The scores of all related items are summed to calculate the score of the questionnaire. Minimum and maximum scores in the areas of care in treatment (9-45), willingness to participate in treatment , ability to adapt , integration of treatment with life (5-25), clinging to treatment (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20), commitment to treatment , and prudence in the implementation of treatment (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) are calculated. The total score range of the questionnaire is from 40 to 200.…”

Section: Research Tools Treatment Adherence Questionnaire (Taq)mentioning

confidence: 99%

“…Since IHD is a chronic disease with no definitive cure, it is essential to manage the disease throughout the patient's life. In addition to the medication, treatment adherence is essential to prevent disease progression and recurrence (11). Patients' lack of adherence or poor treatment adherence is one of the main reasons for treatment failure, increased disease complications, prolonged treatment, increased costs of care, and even devaluation of the best treatment regimens (12).…”

mentioning

confidence: 99%

The Impact of Intervention Based on Protection Motivation Theory on Treatment Adherence in Patients with Ischemic Heart Disease

Zakipoor

Hajalizadeh

Seirafi

et al. 2022

Hormozgan medical journal

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Background: Patients with ischemic heart disease (IHD) gradually reduce their follow-up treatment due to the vulnerable physical condition and high involvement with the disease-related treatment process. The purpose of this research was to investigate the effect of intervention based on the protection motivation theory (PMT) on treatment adherence in patients with IHD. Methods: This quasi-experimental research used a pretest-posttest design with a control group. The statistical population included all patients with IHD referred to the Payambar Azam hospital in Bandar Abbas, Iran for more than once between March 2019 and May 2020. A total of 16 patients were selected through the matched targeted sampling and randomly assigned into two equal groups of experimental and control (n = 8 each). The test group received an intervention based on the PMT in six 90-minute sessions within 45 days. We used the Modanloo Treatment Adherence Questionnaire (TAQ), and the data were analyzed using the analysis of covariance (ANCOVA) in the SPSS23 statistical software. Results: The results of ANCOVA showed that the intervention based on the PMT significantly increased the treatment adherence and its subscales in patients with IHD (P<0.001). Conclusion: Intervention based on the PMT can be used as an effective intervention to increase treatment adherence in patients with IHD, depending on proper nutrition training, self-care skills, awareness-raising, and relaxation exercises.

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“…В результате значительная часть больных, а именно практически каждый шестой пациент, оказались неприверженными к лечению. При этом приверженность больных моложе 60 лет была выше, чем у более возрастных пациентов (отношение шансов (OR) 2,15) [19].…”

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The role of compliance in the treatment of chronic heart failure and the ways to improve it

Мещерина¹,

Хардикова²,

Горшунова³

et al. 2021

Humans and their Health

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Despite the development and implementation of clinical guidelines, emergence of modern effective drugs for the treatment of chronic heart failure (CHF), this pathology is characterized by stable progression, directly worsening the quality of life and decreasing the life expectancy. With that, treatment efficacy directly depends on high treatment compliance in patients with CHF both at the treatment start and upon its subsequent correction. One should also not underestimate the value of patient readiness to modify their lifestyle. Besides, the complete physician compliance with clinical guidelines also plays a significant role. The absence of correspondence between principles defined in the guidelines and really administered drugs excludes the possibility of achieving control over CHF symptoms and positive impact on the prognosis. This review is aimed at evaluating treatment compliance among both patients with CHF and their physicians with a focus on Russian studies and good clinical practice (GCP) compared to studies of foreign authors. Unfortunately, the problem of compliance in CHF in the Russian Federation has not been sufficiently analyzed in large-scale studies up to the present time: CHF patient registries mainly allow to detect clinical and epidemiological disease features, while almost not covering compliance issues. It should also be noted that the problem of compliance in both physicians and patients is undoubtedly up-to-date, as it often defines further prognosis in patients with CHF, which explains the scientific practical value of large trials with subsequent thorough analysis and searches regarding increasing its efficiency.

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Directly Measured Adherence to Treatment in Chronic Heart Failure: LEVEL-CHF Registry

Cited by 8 publications

References 29 publications

Objectively measured medication adherence using assays for carvedilol and enalaprilat in patients with heart failure in Mozambique and Nigeria

Objectively measured medication adherence using assays for carvedilol and enalaprilat in patients with heart failure in Mozambique and Nigeria

The Impact of Intervention Based on Protection Motivation Theory on Treatment Adherence in Patients with Ischemic Heart Disease

The role of compliance in the treatment of chronic heart failure and the ways to improve it

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