Direkte Mischungsanalyse mit hochauflösenden Massenspektrometern — MS/MS*

Green, B. N.; Bateman, Robert; Tümmers, M.; Smith, David C.

doi:10.1007/bf00488189

Cited by 13 publications

(3 citation statements)

References 14 publications

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“…Artifact Peaks jn Parent Ion Tandem Mass Spectra Obtained on a Hybrid Geometry Instrument Sir: Hybrid geometry instruments combine magnetic (B) and electric (E) sectors with quadrupole (Q) mass filters in an instrument designed for experiments in tandem mass spectrometry (MS/MS) (1)(2)(3). Commercial hybrid instruments involve the addition of a collision quadrupole and an analyzing quadrupole to double-focusing instruments of forward (EB) or reverse (BE) geometry.…”

Section: Correspondencementioning

confidence: 99%

“…Sir: Isotope-induced shifts in nuclear magnetic resonance (NMR) spectra have been generally observed and widely utilized for the studies of structure determinations and reaction mechanisms (1)(2)(3)(4)(5). Examples are 2H-and 180-isotope shifts in 13C NMR and 180-isotope shifts in 31P NMR spectra.…”

Section: Literature Citedmentioning

confidence: 99%

“…Acetonitrile for a kinetic solvent was purified and dried, under nitrogen, successively: (1) Commercial acetonitrile was distilled and a central fraction was stored over 3A or 4A Molecular Sieves at least 3 days. (2) The acetonitrile was distilled with a longer column by the addition of a small amount of phosphorus pentoxide and stored over washed and reactivated Molecular Sieves.…”

Section: Literature Citedmentioning

confidence: 99%

See 2 more Smart Citations

Artifact peaks in parent ion tandem mass spectra obtained on a hybrid geometry instrument

DiDonato¹,

Busch²

1986

Anal. Chem.

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Section: Correspondencementioning

confidence: 99%

Section: Literature Citedmentioning

confidence: 99%

Section: Literature Citedmentioning

confidence: 99%

See 1 more Smart Citation

Artifact peaks in parent ion tandem mass spectra obtained on a hybrid geometry instrument

DiDonato¹,

Busch²

1986

Anal. Chem.

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Linked‐scan techniques for MS/MS using tandem‐in‐space instruments

Boyd

1994

Mass Spectrometry Reviews

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Witness this army, of such mass and charge" Shakespeare, W.; Hamlet, 1601, Act IV, Scene 4, line 47. CCC 0277-7037/95/05/60359-52 LINKED-SCAN TECHNIQUES FOR MS/MS FIGURE 2. One-dimensional spectra for ions formed from decane, cxtracted from the complete two-dimensional MSiMS domain shown in Fig. I . Such one-dimensional spectra could be obtained by appropriate single scans, without obtaining all the information exhibited in thc full MS/MS domain. Full circles denote ions whose m i z values are fixed by the conditions of the experiment. and open circles denote ions whose m l i values are to be obtained from the appropriate one-dimensional scan. Reproduced from Ref. (2), by permission.appropriate kinds, without generating the complete MS/MS domain. This review is concerned with the experimental methods for generating such scans, using some common mass spectrometer designs. A more fundamental comment on maps like Fig. 1 concerns the significance of the observation. or not, of any particular reaction. Any such observation strictly refers only to the reaction timescale and other conditions pertinent to the particular apparatus in use. For example, the fact that the ion at m/z 43 was observed ( Fig. 2) to arise from the ion at m / z 85, as well as from the ion at m/z 71, does not necessarily imply that the direct (single-step) reaction (m/z 85+ 43) does occur. The only valid conclusion is that some ions of m/z 85, extracted from the ion source, can fragment to yield m/z 43, but whether or not all such events involve an intermediate at m/z 7 1 cannot be determined from these experiments alone. It is also important to note that the great majority of MS/MS experiments investigate fragmentation reactions (m, < m, , where m, is the molecular mass of species X ) . However, at the lower collision energies characteristic of quadrupole instruments, it is also possible to induce chemical reactions between the reactant ion and a suitable collision gas, such that m, > m,. LINKED-SCAN TECHNIOUES FOR MS/MSFIGURE 3. Schematic representations of the action of (a) magnetic and (b) electric sector fields. In each case. 0 is the subject slit (length dimension perpcndicular 10 the plane of the paper. closeable in the plane). The angular spreads of the ion beam in the plane (which is perpendicular to the magnetic field direction, but contains the electric field lines) are a,,, and a,, respectively. (a) F,,? F , , F2, and F3 are the respective direction focus points for ions of mass m, and velocity u , [Eq. (28)]. mass (m, + 8m) and velocity u , , mass m R , and velocity [Eq. (28)] ( u , + Su), and mass (m,< + Sm) and velocity ( u , + 6u). Thus. the differences between F,, and F,. and between Fz and F2, represent the effective mass dispersion of the magnet. The differences between F,, and F2, and between F, and F; reflect the velocity dispersion. (b) F,, is the direction focus point for ions with any combination of m and u consistent with a kinetic energy ke) [Eq. (30)]. and F, is thc direction focus point [Eq. (30)] for ions with a kinetic...

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A comparison of three experimental techniques for ion structure studies via collision‐induced reactions: The [C₅H₈]⁺˙ example

Curtis¹,

Brenton²,

Bcynon³

et al. 1987

Org. Mass Spectrom.

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Structure differentiation between [C,H,]+' ions, formed by electron ionization of various precursors, has been used as a test case for comparison of three experimental techniques involving collision-induced dissociation (CID).Low-energy CID in an rf-only quadrupole collision cell has been studied in the range 1-150 eV laboratory collision energy. These data have been compared with those obtained using mass-analyzed ion kinetic energy spectroscopy at 8 keV energy, and with results from dissociative charge-stripping (DCS) coupled with a second electron capture collision (EC) in order to remove intense interferences (DCWEC). The greatest degree of structure differentiation was possible using the DCS/EC technique. The other two methods were comparable in this regard, although effects of pre-collision internal energy was apparent for collision energies much below 30 eV. Day-to-day reproducibility of spectra was most difficult to obtain for the low-energy CID technique. Of the [C,H,]+' ions thus tested, the isoprene molecular ion was clearly the best match to the fragment ion formed from limonene.

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Direkte Mischungsanalyse mit hochauflösenden Massenspektrometern — MS/MS*

Cited by 13 publications

References 14 publications

Artifact peaks in parent ion tandem mass spectra obtained on a hybrid geometry instrument

Artifact peaks in parent ion tandem mass spectra obtained on a hybrid geometry instrument

Linked‐scan techniques for MS/MS using tandem‐in‐space instruments

A comparison of three experimental techniques for ion structure studies via collision‐induced reactions: The [C₅H₈]⁺˙ example

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Direkte Mischungsanalyse mit hochauflösenden Massenspektrometern — MS/MS*

Cited by 13 publications

References 14 publications

Artifact peaks in parent ion tandem mass spectra obtained on a hybrid geometry instrument

Artifact peaks in parent ion tandem mass spectra obtained on a hybrid geometry instrument

Linked‐scan techniques for MS/MS using tandem‐in‐space instruments

A comparison of three experimental techniques for ion structure studies via collision‐induced reactions: The [C5H8]+˙ example

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A comparison of three experimental techniques for ion structure studies via collision‐induced reactions: The [C₅H₈]⁺˙ example