2011
DOI: 10.1590/s0103-507x2011000200005
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Diretrizes para tratamento da sepse grave/choque séptico: abordagem do agente infeccioso - diagnóstico

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Cited by 11 publications
(8 citation statements)
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References 108 publications
(106 reference statements)
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“…These guidelines include up-todate information emphasizing the optimization of prescribing antimicrobials with pharmacokinetics and pharmacodynamics considerations, possible de-escalation and complementary aspects aimed at improved clinical outcomes with reduced exposure and lower risks of developing bacterial resistance. (29,30) Because of the increasing problem of microbial resistance, one should search for strategies that prioritize the rational use of resources. The most relevant aspects we frequently overlook in treating severe infection patients are summarized in Chart 3.…”
Section: Commentsmentioning
confidence: 99%
“…These guidelines include up-todate information emphasizing the optimization of prescribing antimicrobials with pharmacokinetics and pharmacodynamics considerations, possible de-escalation and complementary aspects aimed at improved clinical outcomes with reduced exposure and lower risks of developing bacterial resistance. (29,30) Because of the increasing problem of microbial resistance, one should search for strategies that prioritize the rational use of resources. The most relevant aspects we frequently overlook in treating severe infection patients are summarized in Chart 3.…”
Section: Commentsmentioning
confidence: 99%
“…Em decorrência dessas alterações, tem-se observado um aumento da demanda dos serviços de saúde. Em geral, os idosos são portadores de múltiplas patologias crônicas, consomem mais serviços de saúde por necessitarem de cuidados prolongados, passam por internações hospitalares com mais frequência, sendo o tempo de ocupação do leito maior do que o de outras faixas etárias 3 , além de intervenções contínuas e maior demanda por leitos de unidades de terapia intensiva (UTI) 4 . Nesse sentido, verifica-se que, entre os pacientes admitidos em UTI, os idosos são responsáveis por 42 a 52% das admissões e consomem cerca de 60% das diárias disponíveis.…”
Section: Introductionunclassified
“…The empirical use of antibiotic therapy is essential for a good prognosis of the patient. Before administration, it is important to perform cultures to identify the etiologic agent of the infection, thus being able to adapt the antibiotic therapy to cover pathogens resistant to the initial empirical scheme or to de-escalate the antimicrobial from the empirical therapy, reducing the cost of treatment, diminishing the side effects, and avoiding bacterial resistance 13 . In this study, 29.4% of the patients were using antimicrobials for empirical treatment of pneumonia not associated with mechanical ventilation and only 16.5% used antimicrobials guided by culture results.…”
Section: Discussionmentioning
confidence: 99%