Diruthenium aryl compounds – tuning of electrochemical responses and solubility

Abstract

The variation of the substituents (X = 3,5-(OMe)2; 3-iPrO) on the bridging ligand results in improved solubility of Ru2-aryl compounds, while the aryl substitution significantly influences the potentials of the Ru2-based redox couples.

Charge effect in protein metalation reactions by diruthenium complexes

“…The synthesis and reactivity of these complexes have been intensively studied in the last few years due to their singular electrochemical 10,11 and magnetic properties. 12–16 Diruthenium( ii , iii ) paddlewheel complexes have also been used as scaffolds to prepare anticancer agents 17–25 and to produce stable metalloenzymes with fascinating catalytic properties.…”

“…3,4 Besides carboxylates, a variety of N,O-and N,N′-bridging bidentate ligands have been employed to obtain diverse diruthenium motifs. [5][6][7][8][9] The synthesis and reactivity of these complexes have been intensively studied in the last few years due to their singular electrochemical 10,11 and magnetic properties. [12][13][14][15][16] Diruthenium(II,III) paddlewheel complexes have also been used as scaffolds to prepare anticancer agents [17][18][19][20][21][22][23][24][25] and to produce stable metalloenzymes with fascinating catalytic properties.…”

New insights into progressive ligand replacement from [Ru2Cl(O2CCH3)4]: synthetic strategies and variation in redox potentials and paramagnetic shifts

“…Since then, many diruthenium complexes with a large variety of donor bridging ligands, such as other O,O′donors (carboxylates), 3 O,N-donors (amidates 4 or hydroxypyridinates 5 ) or N,N′-donors (such as amidinates 6 or anilinopyridinates 7 ), have been investigated. In this regard, it is worth mentioning the high stability of these formally mixed-valence species (actually, they are average valence species) and the variety of structural arrangements, 8 which provides these compounds with exceptional magnetic, [9][10][11][12] electronic, 13,14 and electrochemical [15][16][17] behaviours. These properties, as well as the ability of the diruthenium core to coordinate different chemical species through their axial, 13,18,19 equatorial 6,[20][21][22][23] or peripheral positions, 24,25 make these compounds suitable for many potential applications, such as catalysis, [26][27][28][29] biological chemistry (anticancer activity and 30,31 interaction with proteins 27,32 ), or electronics (as electronic wires 33 ).…”

Bisaryl and Bisalkynyl Diruthenium (III,III) Compounds Based on an Electron-Deficient Building Block

“…In addition to ap and its fluorinated analogues, two other types of bridging ligands, DArF (DArF = N,N ′-diarylformamidinate, Scheme ) and DMBA (DMBA = N,N ′-dimethylbenzamidinate), have been frequently employed to support Ru 2 (III,III) organometallic compounds. ,− While bisalkynyls Ru 2 (III,III) are attainable with all three types of ligands, the steric requirements enforced by the bridging ligands’ flanking phenyls , has resulted in bisaryls Ru 2 (III,III) only being achieved with DMBA thus far . Hence, the arrangement of dissymmetric N,N ′-bidentate ligands around the Ru 2 core, Scheme , is significant in dictating the number of aryl ligands at the axial positions.…”