250 word max) Aim: Individuals who require manual wheelchairs after stroke are typically taught to ambulate with compensatory propulsion (i.e. using their nonparetic arm and foot), risking disuse of the paretic arm. We investigated whether stroke survivors can instead ambulate in a bimanual, leverdriven wheelchair that requires the paretic arm to contribute half the propulsive input.Methods: Seventeen individuals with chronic stroke and severe hemiparesis (upper extremity Fugl-Meyer scores between 10 and 24) participated across two experiments. In the first experiment participants (n=12) ambulated in straight paths. In the second experiment participants (n=12) also performed turns, using an improved version of the wheelchair that incorporated handbrakes.Twelve unimpaired controls also completed the second experiment. Motion capture and EMG were used to compare biomechanics between groups.Results: Altogether, 15 of 17 participants with stroke could ambulate 30 m in straight paths, and 9 of 12 could turn 1800° entirely under the power of their paretic arm. Participants with stroke exhibited largely healthy biomechanics, with minimal shoulder hiking/leaning or trunk inclination.Their arm muscle EMG patterns were similar to those used by unimpaired participants, excepting delayed elbow extensor activation.Conclusions: Individuals with severe arm impairment in the chronic stage of stroke retain sufficient strength and coordination with their paretic arm to maneuver bimanual, lever-driven wheelchairs. We suggest bimanual, lever driven propulsion should be explored in stroke rehabilitation practice as an alternative to compensatory wheelchair propulsion, as it has the potential to exercise healthy movement synergies, which may in turn help drive use-dependent motor recovery.