Disappearance of colorectal polyps is rare. 1 Here, we report the disappearance of a large pedunculated polyp. A 58-year-old man with suspected colonic diverticular bleeding was referred to our hospital owing to recurrent hematochezia, despite a hemoclip placement on the diverticulum, which was suspected to be the bleeding source. The patient's medical history was unremarkable, and he was not under medication. Emergency endoscopy after oral bowel preparation revealed multiple diverticula and an approximately 25-mm pedunculated adenomatous polyp in the descending colon. A clip was found at the base of the polyp (Fig. 1a,b) with no obvious evidence of active bleeding. Additional clips were used to prevent hemostasis. However, on the next day, the patient presented with recurrent hematochezia. His blood pressure was 105/61 mmHg, with a pulse rate of 77 beats/min and hemoglobin level of 8.1 g/dL. Enhanced computed tomography revealed active extravasation in the descending colon, and emergency angiography was performed to stop the bleeding. Interventional radiology revealed active bleeding on angiography at the site of the clip. Selective embolization of the left colic marginal branch artery was performed using a coil (Fig. 1c,d). No bleeding was observed after embolization. Two months later, the patient underwent endoscopy to resect the colonic polyp. The large pedunculated polyp,