Disappearing nodules: spontaneously regressing pulmonary amyloidosis

Glass, Lisa N; Sumon, Mahbubur; Goulart, Hannah; Ahari, Jalil

doi:10.1136/bcr-2019-229718

Cited by 1 publication

(2 citation statements)

References 13 publications

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“…The favourable clinical and radiological evolution with the disappearance of all symptoms, including dyspnoea and cough, was atypical. Although reports have shown that secondary amyloidosis can completely resolve with treatment, few cases of pulmonary amyloidosis have spontaneously resolved [14,15] . To our knowledge, our case of pulmonary cystic amyloidosis is unique [14][15][16] .…”

Section: Discussionmentioning

confidence: 99%

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Spontaneous Resolution of a Pulmonary Cystic Amyloidosis Mass

Guediri

Meijri

Boubaker

et al. 2022

European Journal of Case Reports in Internal Medicine

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Introduction: Amyloidosis is a rare illness characterized by the deposition in organs of amyloid, which can be detected by histological staining. Amyloidosis restricted to the lower respiratory tract is unusual. Results: We reported the case of a 68-year-old woman with no history of chronic disease who presented with dyspnoea on exertion, cough and fatigue. The physical examination was unremarkable. A CT scan showed a cystic mass with a thickened wall in the apical segment of the left lower lobe. A biopsy of the mass was performed, and histological and immunohistochemical study confirmed the diagnosis of AL amyloidosis. The patient’s clinical and radiological symptoms spontaneously improved without treatment after 3 years. Conclusion: Amyloid-related cystic lung disease is a rare presentation of amyloidosis in the thorax. More case reports are required to determine if such masses can resolve without treatment and whether amyloid-associated cystic lung disease actually exists.

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Section: Discussionmentioning

confidence: 99%

“…Although reports have shown that secondary amyloidosis can completely resolve with treatment, few cases of pulmonary amyloidosis have spontaneously resolved [14,15] . To our knowledge, our case of pulmonary cystic amyloidosis is unique [14][15][16] .…”

Section: Discussionmentioning

confidence: 99%