The Yangtze River Valley is an important economic region and one of the cradles of human civilization. It is also the site of frequent floods, droughts, and other natural disasters. Conducting Holocene environmental archaeology research in this region is of great importance when studying the evolution of the relationship between humans and the environment and the interactive effects humans had on the environment from 10.0 to 3.0 ka BP, for which no written records exist. This review provides a comprehensive summary of materials that have been published over the past several decades concerning Holocene environmental archaeology in the Yangtze River Valley, to further understand large-scale regional Holocene environmental and cultural interaction within this area. The results show that: 1) in recent years, Holocene envi-ronmental archaeology research in the Yangtze River Valley has primarily taken paleoflood and sea-level change stratigraphical events to be the foundational threads for study. This began with research on the spatiotemporal distribution of archaeological sites, typical archaeological site stratigraphy, and research on background features concerning environmental evolution recorded by the regional natural sedimentary strata. 2) Significant progress has been made at the upper, middle, and lower reaches of the Yangtze River, indicating that Holocene environmental ar-chaeology research along the Yangtze River Valley is deepening and broadening. 3) Dramatic changes to Neolithic cultures that occurred approximately 4.0 ka BP were influenced by climate change and associated consequences, although the impacts differed on the various Neolithic cultures in the Yangtze River Valley. Local topography, regional climate, and varying survival strategies may have contributed to these differences. 4) Newly-published research pays particular attention to the sedimentary records of the past with resolutions as high as one year to several months, the degree to which humans altered the quality of their natural environment, and human adjustments to settlement and subsistence practices during periods of Holocene climate change. The application of technologies such as remote sensing, geographic information systems (GIS), and molecular biological analysis are also gradually being extended into the research field of Holocene environmental archaeology in the Yangtze River Valley.