Quantum coherence and non-Markovianity of an atom in dissipative cavity under weak measurement are investigated in this work. We find that, the quantum coherence obviously depends on the atomic initial state, the strength of the weak measurement and its reversal, the atom-cavity coupling constant and the non-Markovian effecct. The more obvious the weak measurement effect is, the better the protection of coherence is. The quantum coherence is preserved more efficiently for lager the atom-cavity coupling. The stronger the non-Markovian effect, the more slowly the coherence reduces. This is, the quantum coherence can be effectively protected by means of controlling these physical parameters.