Discovering the major metabolites of the three novel fentanyl analogues 3-methylcrotonylfentanyl, furanylbenzylfentanyl, and 4-fluorocyclopropylbenzylfentanyl for forensic case work

Bergh, Marianne Skov-Skov; Bogen, Inger Lise; Nerem, Elisabeth; Wohlfarth, Ariane; Wilson, Steven Ray; Øiestad, Åse Marit Leere

doi:10.1007/s11419-020-00560-9

Cited by 1 publication

(2 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The new non-therapeutic fentanyl analogs have been later described as NPSs or NSOs, seriously affecting the neurological system [ 34 ]. New fentanyl analogs are reported from year to year; for example, three of them appeared on the European market in 2018: 3-methylcrotonylfentanyl, furanylbenzylfentanyl, and 4-fluorocyclopropylbenzylfentanyl (structure shown in Table 1 ) [ 40 ].…”

Section: Introductionmentioning

confidence: 99%

“…There are many non-therapeutic fentanyl analogs reported to the United Nations Office on Drugs and Crime Early Warning Advisory (UNODC EWA), which are common in Europe, Asia, and America [ 5 , 29 , 40 ]. The United States Drug Enforcement Agency (DEA) listed fentanyl and its derivatives (isomers, thioethers, and salts) in the Schedule I list [ 41 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Electroanalysis of Fentanyl and Its New Analogs: A Review

et al. 2022

View full text Add to dashboard Cite

The review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The review also covers the analysis of new synthetic opioids, their parent compounds, and corresponding metabolites in body fluids, such as urine, blood, serum, and plasma, necessary for a fast and accurate diagnosis of intoxication. Identifying and quantifying these addictive and illicit substances and their metabolites is necessary for clinical, toxicological, and forensic purposes. As a reaction to the growing number of new synthetic opioid intoxications and increasing fatalities observed over the past ten years, we provide thorough background for developing new biosensors, screen-printed electrodes, or other point-of-care devices.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%