Discovery and Development of Gaseous Nitric Oxide Under Increased Atmospheric Pressure as an Antimicrobial

Gaseous nitric oxide failed to inhibit the replication cycle of SARS-CoV-2 in vitro

“…This molecule is a bactericidal compound active against a large spectrum of microorganisms: gram-positive and gram-negative bacteria, yeast, mycobacteria … [ 4 ]. At high dosages (160 ppm), NO gas has been considered as a potent bactericidal agent to treat a broad array of pulmonary infections, including nosocomial pneumonia or infections caused by multi-drug resistant bacterial strains [ 5 , 6 ]. In a study led by Miller, pulmonary cells infected with different bacterial strains (S. aureus, P. aeruginosa, E.…”