“…17,[19][20][21][22][23] Among FET-based biosensors, AlGaN/GaN high electronmobility transistor (HEMT) stands out as a more suitable choice for bio-sensing due to its non-toxicity, biocompatibility, and chemical stability. [24][25][26][27][28][29] Above all, the two-dimensional electron gas (2DEG) in the AlGaN/GaN HEMT sensor is a located in close proximity to the surface, rendering it highly responsive to variations in surface potential. In recent years, AlGaN/GaN HEMT sensors have been successfully employed for the detection of proteins (biomarkers, antigens), [30][31][32] ions, 29,[33][34][35][36] DNA hybridization, 37 and pH [38][39][40][41] in solution or serum samples due to their various advantages mentioned above.…”