Discovery of Glucose Metabolism-Associated Genes in Neuropathic Pain: Insights from Bioinformatics
Ying Yu,
Yan-Ting Cheung,
Chi-Wai Cheung
Abstract:Metabolic dysfunction has been demonstrated to contribute to diabetic pain, pointing towards a potential correlation between glucose metabolism and pain. To investigate the relationship between altered glucose metabolism and neuropathic pain, we compared samples from healthy subjects with those from intervertebral disc degeneration (IVDD) patients, utilizing data from two public datasets. This led to the identification of 412 differentially expressed genes (DEG), of which 234 were upregulated and 178 were down… Show more
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