“…In addition, population variation in TH physiology has been observed in other fishes and may be an important physiological mechanism underlying local population differentiation in energy metabolism or morphology (e.g. Kitano et al ., 2010; Kitano and Lema, 2013; Levin and Bolotovskiy, 2015). Based on the differences in hepatic and muscle dio and tr expression observed here between the Amargosa River and Tecopa Bore C. n. amargosae populations, it is possible that variation in TH signaling, even if only at the level of some target tissues (e.g., Lema and Kitano, 2013), could contribute developmentally to the morphological variation between these populations.…”