New J. Chem.
 2022
DOI: 10.1039/d1nj04927e
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Discovery of novel antifungal resorcylate aminopyrazole Hsp90 inhibitors based on structural optimization by molecular simulations

Yan Tuo
1
,
guangping Li
2
,
Zhou Liu
3
et al.

Abstract: Hsp90 is a highly conserved and essential stress protein located in all eukaryotes, involved in the regulation of fungal survival, virulenceand resistance, which is an important target for the treatment...

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