Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases

Kurz, Sabine; Sido, Viyan; Herbst, Hermann; Ulm, Bernhard; Salkic, Erma; Ruschinski, Thomas M.; Buschmann, C.; Tsokos, Michael

doi:10.1371/journal.pone.0255490

Cited by 20 publications

(13 citation statements)

References 24 publications

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“…Unusual findings can only be noted after the PE in a form of permanent documentation of pathologies identified at autopsy [ 2 ]. An autopsy is mandatory for retrospective quality assessment of clinical diagnosis [ 27 ] as an essential source of material for medical undergraduates and postgraduate teaching [ 28 ].…”

Section: Reviewmentioning

confidence: 99%

“…Start et al are in strong disagreement with the suggestions that advances in diagnostic techniques have diminished the role of autopsies [ 28 ]. PE in autopsy is essential for retrospective quality assessment of clinical diagnosis by Kurz et al [ 27 ]. Histopathological diagnosis on autopsy correlated well with the clinical COD by Khare et al [ 1 ].…”

Section: Reviewmentioning

confidence: 99%

“…Hansen stated that regular autopsy does not reveal the desired findings; hence, it needs to adjunct with clinical history and protocol-based grossing for PE of heart in autopsy cases [ 7 ]. Hansen, Kurz et al, and Basso et al supported the protocol-based forensic pathologist training [ 7 , 27 , 56 ].…”

Section: Reviewmentioning

confidence: 99%

“…Zaitoun et al concluded in their study that autopsy histology is the most accurate method for determining the COD and auditing the accuracy of clinical diagnoses[5].Start et al are in strong disagreement with the suggestions that advances in diagnostic techniques have diminished the role of autopsies[28]. PE in autopsy is essential for retrospective quality assessment of clinical diagnosis by Kurz et al[27]. Histopathological diagnosis on autopsy correlated well with the clinical COD by Khare et al[1].…”

mentioning

confidence: 99%

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A Comprehensive Review of Pathological Examination in Forensic Medicine: Past, Present, and Future

Singh¹,

Tiwari²,

Kumar³

et al. 2022

Cureus

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Pathological examination (PE) encompasses a gross or macroscopy and histopathological or microscopic examination. It is prudent in finding the cause of death (COD) in clinical and medicolegal autopsies. There are various auxiliary techniques in the form of clinical history, communication, specialized training, and protocols for consolidation of the PE results. After a thorough search of the literature in PubMed with relevant keywords along with further analysis of the results, it emerged that even with the modernization of forensic medicine, a PE is unbeatable in detecting the COD. It has various useful aspects, apart from regular finding the COD, such as in student teaching, epidemiology of disease, audit tool, and quality assurance. There are also limitations of PE, which should be dealt with great caution. Hence, limitations must be understood by a forensic expert as well as a pathologist. In this review, all factors that are related to PE in any manner are discussed in detail, and the scope for improving the quality of PE to be relevant in the present scenario is reviewed. It is a comprehensive reassessment of the literature review that also casts light on the future along with a critical analysis of the facts that deal with PE.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

A Comprehensive Review of Pathological Examination in Forensic Medicine: Past, Present, and Future

Singh¹,

Tiwari²,

Kumar³

et al. 2022

Cureus

View full text Add to dashboard Cite

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“…Autopsy is not only the patient's final medical treatment; in addition to identifying the reasons of death, but it also sheds light on the underlying condition of the patient who has passed away. Clinical autopsies require either the deceased's antemortem consent or the family' post-mortem consent which is in contrast to forensic autopsies (1). The majority of clinicians and pathologists continue to view autopsies as necessary, with discrepancy rates between premortem and post-mortem diagnoses remaining constant over the years at around 10%.…”

Section: Introductionmentioning

confidence: 99%

Classification of Post-Mortem Changes and Factors Affecting It

Emam¹,

Mujalid²,

Altamimi³

et al. 2022

JOHS

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An autopsy is not simply the patient's last medical intervention but in addition to determining the cause of death, it also provides information about the deceased patient's underlying health. The natural process of the body's breakdown following death, starting at the cellular level, is known as post-mortem change. Complex cellular and biochemical phenomena are involved in the process. The changes that begin right away after death continue for a considerable amount of time at various rates for various organs. Numerous intrinsic and extrinsic factors have an impact on the beginning and severity of these changes. The purpose of this research is to review the available information about classification of post-mortem changes and factors affecting it. Post-mortem changes are further divided into three classes, Immediate changes, early changes and late changes. After cardiac and respiratory failure, early post-mortem changes including rigor mortis and post-mortem lividity occur. However, tissue metabolism continues for a few hours after death. Supravital reactions, time-dependent post-mortem lividity, and rigor mortis criteria are used to estimate the time since death. Estimating the post-mortem interval or time since death, is one of the main aims of the forensic autopsy, requires an understanding of post-mortem changes. Many exogenous and endogenous factors can lead to degradation. Animal predation, the environment, and mechanical injury are extrinsic causes, whereas autolysis, putrefaction, and decay are endogenous factors. However, despite the importance of post-mortem findings the literature available is very limited more research in future can be a significant contributor.

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