Via a generalization of the pseudospectral method for numerical solution of differential equations, a family of nonlinear algebraic identities satisfied by the zeros of a wide class of orthogonal polynomials is derived. The generalization is based on a modification of pseudospectral matrix representations of linear differential operators proposed in the paper, which allows these representations to depend on two, rather than one, sets of interpolation nodes. The identities hold for every polynomial family { ] ( )} ∞ ]=0 orthogonal with respect to a measure supported on the real line that satisfies some standard assumptions, as long as the polynomials in the family satisfy differential equations A ] ( ) = ] ( ) ] ( ), where A is a linear differential operator and each ] ( ) is a polynomial of degree at most 0 ∈ N; 0 does not depend on ]. The proposed identities generalize known identities for classical and Krall orthogonal polynomials, to the case of the nonclassical orthogonal polynomials that belong to the class described above. The generalized pseudospectral representations of the differential operator A for the case of the Sonin-Markov orthogonal polynomials, also known as generalized Hermite polynomials, are presented. The general result is illustrated by new algebraic relations satisfied by the zeros of the Sonin-Markov polynomials.