Discrete-Phase Modelling of an Asymmetric Stenosis Artery Under Different Womersley Numbers

Prashantha, B; Anish, S.

doi:10.1007/s13369-018-3391-z

Cited by 4 publications

(2 citation statements)

References 45 publications

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“…Hossain and Haque [17] stated that overlapping stenosis has caused more CVDs than the single stenosed artery. Prashantha and Anish [23] agreed with [17] by highlighting that around 70 to 80% of CVDs occur in geometries which are complex such as in an overlapping stenosed artery. According to Freidoonimehr et al [14], the shape as well as the degree of stenosis of a stenotic coronary artery have crucial impacts on the arterial blockage.…”

Section: Introductionmentioning

confidence: 68%

Exact Analysis of Unsteady Solute Dispersion in Blood Flow: A Theoretical Study

Abidin,

Jaafar,

Ismail

2023

MJMS

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The diameter of an artery can narrow due to atherosclerosis or stenosis, making it challenging to resolve solute dispersion issues as blood flows via a stenosed artery. The stenosis occurrence restricted drug dispersion and blood flow. This research introduces the establishment of a mathematical model in examining the unsteady dispersion with respect to the solute in overlapping stenosis arteries depicting blood as a Herschel-Bulkley (H-B) fluid model. Note that fluid velocity was obtained by analytically solving the governing and constitutive equations. The transport equation has been solved by employing a generalised dispersion model (GDM), in which the dispersion process is described. Accordingly, yield stress, stenosis height, slug input of solute length, as well as a rise in the power-law index have improved the peak with regard to the mean concentration and solute concentration. The maximum mean concentration yielded the effective dose for therapeutic concentration. In conclusion, this study is relevant to disease arteries, coagulating hemodynamics and may help physiologists in furnishing a more refined understanding of diffusion processes in cardiovascular hydrodynamics. An interesting application related to the present study is the transportation of drugs in the arterial blood flow.

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Section: Introductionmentioning

confidence: 68%

Exact Analysis of Unsteady Solute Dispersion in Blood Flow: A Theoretical Study

Abidin,

Jaafar,

Ismail

2023

MJMS

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“…According to Hossain and Haque [23] and Freidoonimehr et al [24], the shape and degree of stenosis of a stenotic coronary artery have significant impacts on arterial blockage. Prashantha and Anish [25] emphasized the importance of understanding haemodynamics in the post-stenotic of asymmetric stenosis. The authors highlighted that about 70 to 80% of cardiovascular diseases occur in complex geometries.…”

Section: Introductionmentioning

confidence: 99%

Herschel-Bulkley Model of Blood Flow through an Asymmetric Stenosed Artery on Unsteady Reactive Solute Dispersion

Zainul Abidin,

Jaafar,

Ismail

2022

MATEMATIKA

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This study examined the effects of chemical reaction, stenosis shape parameter and non-Newtonian behaviour on solute dispersion in blood flow via an asymmetric stenosed artery using the generalised dispersion model (GDM). The Herschel–Bulkley (H-B) fluid model, which consists of a yield stress and power-law index, is used to represent the non-Newtonian characteristics of blood in a narrow artery at a low shear rate. The impact of stenosis shape parameter, chemical reaction, power-law index and plug flow radius on the dispersion coefficient and effective axial diffusion of solute is shown. The findings showed that the aforementioned parameters significantly impact the overall process of the chemically reactive solute in a bulk flow. The dispersion coefficient and effective axial diffusion decreases with an increase in the chemical reaction rate, stenosis shape parameter and power-law index. As time passes, the dispersion process slows and becomes almost constant implying a steady state of diffusion. In short, this study provides further insights into the physiological processes involved in the dispersion of drugs and nutrients in the circulatory system.

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