“…Therefore, a data-driven optimization model emerges. Huang et al (2019) [7] proposed a Data-Driven Optimization Model (DDOM) to describe the relationship between energy consumption and the discrete speed profile, then integrated two typical machine learning algorithms, Random Forest Regression (RFR) and Support Vector machine Regression (SVR), into a heuristic algorithm to solve the model. Similarly, much research has been associated with the train timetable optimization problem in rail transportation systems (Shakibayifar et al, 2017 [18], Wang et al, 2017 [19], Gainanov et al, 2017 [20], Hassannayebi et al, 2018 [21]).…”