2010
DOI: 10.1186/1471-2105-11-s1-s50
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Discrete wavelet transform de-noising in eukaryotic gene splicing

Abstract: BackgroundThis paper compares the most common digital signal processing methods of exon prediction in eukaryotes, and also proposes a technique for noise suppression in exon prediction. The specimen used here which has relevance in medical research, has been taken from the public genomic database - GenBank.MethodsHere exon prediction has been done using the digital signal processing methods viz. binary method, EIIP (electron-ion interaction psuedopotential) method and filter methods. Under filter method two fi… Show more

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Cited by 33 publications
(30 citation statements)
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“…When [ ] is plotted against K, [15] it reveals a peak at N/3 for a coding region and no such peak is observable for a noncoding region. In rectangular windows with length 240 were used for evaluating the STDFT of the gene F56F11.4 in C.elegans chromosome III over the bases 7021 to 15120 as show in Fig 10. This 8100-length DNA sequence, which obtained using the Nucleotide Accession Number " F099922" at Genbank website [16], contains five known coding regions.…”
Section: Eiip Representationmentioning
confidence: 99%
See 1 more Smart Citation
“…When [ ] is plotted against K, [15] it reveals a peak at N/3 for a coding region and no such peak is observable for a noncoding region. In rectangular windows with length 240 were used for evaluating the STDFT of the gene F56F11.4 in C.elegans chromosome III over the bases 7021 to 15120 as show in Fig 10. This 8100-length DNA sequence, which obtained using the Nucleotide Accession Number " F099922" at Genbank website [16], contains five known coding regions.…”
Section: Eiip Representationmentioning
confidence: 99%
“…The Fourier power spectrum of the Voss"s binary indicator sequences, reveals a peak at frequency 1/3 (period-3) for coding regions and shows no peak for non-coding regions. The main application of Voss technique is the efficient identification of the coding and non-coding regions in a DNA sequences [15]. DFT of a sequence ( ) of length L, is itself another sequence [ ], of the same length L.…”
Section: Voss Mapping Techniquementioning
confidence: 99%
“…The wavelet transform plot was used to pinpoint the location of the mutation in gene sequence [14]. George [15] explains lossless and lossy schemes in DWT and its application in gene segregation. DWT based EIIP technique was implemented in cancer prediction [16].…”
Section: Introductionmentioning
confidence: 99%
“…The models provide an input for continuous complex wavelet transform that is a promising tool for detection of (short) coding regions in DNA due to a possibility to optimize frequency-position resolution within DNA. Multiresolution signal processing methods have been used in genomics in a number of applications [4]: gene mutation detection [5], denoising [6], exon detection [7], and many others.…”
Section: Introductionmentioning
confidence: 99%