To solve the problem of low-frequency noise in the environment, a Helmholtz-type phononic crystal with adjustable cavity structure and labyrinth tubes was designed. The unique design of the labyrinth tube greatly increases the length of the tube, improving low-frequency sound insulation performance, and the design of adjustable cavity structure realizes active regulation of the band structure. The band gap structure and sound insulation characteristics were analyzed by finite element method (FEM) and electro-mechanical-acoustic analogy method. The result shows that, firstly, the structure can generate two complete band gaps in the low-frequency range of 0–500 Hz, and there is a low-frequency band gap with lower limit of 40 Hz. Meanwhile, the structure has excellent sound insulation performance in the range of 0–500 Hz. Secondly, multiple resonant band gaps can be connected by adjusting the structural layout of the cavity through the telescopic screw, so as to achieve the purpose of widening the band gap and active control of environmental noise. Finally, in the periodic arrangement design of the structure, reducing the spacing between cells can effectively increase the bandwidth of band gaps. This design broadens the design idea of phononic crystal and provides a new method to solve the problem of low-frequency noise control.