Discriminating ability of spectral domain optical coherence tomography in different stages of glaucoma

Abstract

RNFL thickness measured with SD-OCT could discriminate the three stages of glaucoma. RNFL loss can be correlated to visual field loss. Future OCT-based staging of glaucoma, adjunctive to perimetry is possible.

Correlation of Average Retinal Nerve Fiber Layer Thickness Using OCT with the Perimetric Staging in Primary Open Angle Glaucoma

“…Moreover, this present study data are in accordance with another study in which they noted that normal controls had significantly higher RNFL thickness when compared with glaucoma patients and those with more severe disease had significantly thinner RNFL (6) .…”

“…Finally, the present study found that RNFL thickness has a good diagnostic value for diagnosis of glaucoma and for differentiating moderate from mild glaucoma and severe from moderate glaucoma. This is in agreement with the study of Elbendary and Helal (6) and with a recent metaanalysis performed by Michelessi et al (12) . The authors included prospective and retrospective cohort studies and case-control studies that evaluated the accuracy of OCT for diagnosing glaucoma.…”

A combination of topographic and pachymetric parameters in keratoconus diagnosis

“…The diagnostic power of the each Scheimpflug parameter was graded according to the AUC value as follows; excellent (0.90-1.00), good (0.80-0.89), fair (0.70-0.79), poor (0.60-0.69) and worthless (0.50-0.59). The ROC curve plots the true positives (sensitivity) against the false positives (100-specificity) for different threshold values [14]. Values on the ROC curve, which indicated best sensitivity-specificity pair, were accepted as the cut points [14].…”

“…The ROC curve plots the true positives (sensitivity) against the false positives (100-specificity) for different threshold values [14]. Values on the ROC curve, which indicated best sensitivity-specificity pair, were accepted as the cut points [14]. At 95% confidence interval, a P value less than 0.05 was considered statistically significant.…”

Macular Ganglion Cell–Inner Plexiform Layer and Retinal Nerve Fiber Layer Thickness in Eyes With Primary Open-Angle Glaucoma Compared With Healthy Saudi Eyes

“…In 30 normal Egyptian eyes, the RNFL thickness was 110 μm, and in 150 glaucomatous eyes, it was 80 μm. 21 Thus, even among Arabs, RNFL thickness varied between the Saudi and Egyptian communities. In normal and glaucomatous eyes of the Arab population, macular thickness parameters measured by OCT are presented perhaps for the first time in our study.…”